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Record W4416356211 · doi:10.1016/j.jaccas.2025.106125

Radiofrequency Ablation and Right Purkinje De-Networking for Moderator Band PVC-Induced VF

2025· article· en· W4416356211 on OpenAlexaff
Eduardo Sanhueza, Matthew Hanson, Víctor Neira, Sanoj Chacko, Andrés Enríquez, Jacob Pardy, David Bakker, Roji Oli, Mariana Saramago, Cengiz Burak

Bibliographic record

VenueJACC Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac Arrhythmias and Treatments
Canadian institutionsQueen's University
Fundersnot available
KeywordsRadiofrequency ablationAblationAtrial fibrillationPercutaneousPurkinje fibersElectrocardiography

Abstract

fetched live from OpenAlex

BACKGROUND: Idiopathic ventricular fibrillation (VF) can occasionally be triggered by rare premature ventricular complexes (PVCs), including those from the moderator band. Radiofrequency ablation (RFA) is challenging given low PVC burden and anatomic complexity. CASE SUMMARY: A 36-year-old man with idiopathic VF and an implantable cardioverter-defibrillator for secondary prevention presented with multiple shocks. The VF episodes were triggered by short-coupled PVCs from the moderator band. Despite a low PVC burden (<1%), zero-fluoroscopy catheter ablation was performed. RFA was guided by pace mapping, followed by right-sided Purkinje de-networking. The procedure was uncomplicated, and at 8-month follow-up, the patient remained asymptomatic, with no PVCs or arrhythmic events. DISCUSSION: Low-burden PVC-triggered VF is challenging, as conventional pace mapping is limited. Targeted Purkinje network ablation (de-networking) appears to reduce the risk of recurrent VF. TAKE-HOME-MESSAGE: Pace-mapped RFA combined with ipsilateral Purkinje de-networking may be an effective zero-fluoroscopy strategy for PVC-induced VF, even with low ectopic burden.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.312
Threshold uncertainty score0.517

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.297
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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