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Neural Patterns Reflect Shared Emotional History

2025· article· en· W4416368510 on OpenAlexafffund
Chantelle M. Cocquyt, Isabel Wilson, Daniela J. Palombo

Bibliographic record

VenueJournal of Neuroscience · 2025
Typearticle
Languageen
FieldNeuroscience
TopicMemory and Neural Mechanisms
Canadian institutionsBritish Columbia Centre of Excellence for Women's HealthUniversity of British Columbia
FundersNatural Sciences and Engineering Research Council of CanadaCanada Foundation for Innovation
KeywordsFunctional magnetic resonance imagingEpisodic memoryContext (archaeology)MnemonicPerceptionNeural correlates of consciousnessPrefrontal cortexSimilarity (geometry)Emotional expression

Abstract

fetched live from OpenAlex

Emotions shape episodic memories, with emotional context-the affective quality or "hue" of an experience-persisting as part of the event in memory, scaffolding connections between events, and guiding our impressions of the environment. We propose that events encoded in a similar emotional context also exhibit similar patterns of brain activation during retrieval, particularly when such events are negative. To explore this idea, we scanned 33 human participants of all genders using functional magnetic resonance imaging as they completed a two-phase episodic memory task. During encoding, participants viewed trial-unique image pairs: a neutral object alongside a complex picture evoking either a negative or neutral emotional context. Across conditions, images were closely matched on low-level perceptual features. During retrieval, participants were shown the neutral objects again and rated their pleasantness, implicitly recalling their emotional context. To determine whether there is a neural signature that reflects salient emotional contexts, we employed trial-level representational similarity analysis, focusing on three brain areas previously linked to emotional memory, appraisal, and/or affective schemas: ventral visual stream (VVS), hippocampus, and ventromedial prefrontal cortex (vmPFC). Our results demonstrate strong converging evidence of emotional context coding in the VVS, reflecting a shared signature of negative emotional context across retrieval and reinstatement of encoding activation patterns, particularly for negative events. Meanwhile, the hippocampus and vmPFC played a more nuanced role. These findings reveal that content with a shared emotional context evokes brain activity patterns reflecting the essence of its emotional history, highlighting the brain's flexible capacity to integrate affective content into mnemonic representations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.158
GPT teacher head0.348
Teacher spread0.190 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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