MétaCan
Menu
Back to cohort
Record W4416373747 · doi:10.1016/j.addbeh.2025.108563

Patterns of polysubstance use disorder among human trafficking survivors: A latent class analysis

2025· article· en· W4416373747 on OpenAlexaboutno aff
Nathaniel A. Dell, Jason T. Carbone, Theresa Anasti, Lauren M. Grimes, Kathleen M. Preble, Lindsay B. Gezinski, Hilary Thibodeau

Bibliographic record

VenueAddictive Behaviors · 2025
Typearticle
Languageen
FieldMedicine
TopicSubstance Abuse Treatment and Outcomes
Canadian institutionsnot available
FundersNational Institute on Drug Abuse
KeywordsPolysubstance dependenceLatent class modelIntervention (counseling)Poison controlHuman factors and ergonomicsInjury preventionSuicide preventionQuarter (Canadian coin)Human trafficking

Abstract

fetched live from OpenAlex

• Survivors of human trafficking are at risk for substance use disorder (SUD). • Survivors of human trafficking (HT) are at risk for substance use disorder (SUD). • Our latent class analysis of SUDs among emergency visits involving HT survivors found three distinct groups. • Classes were distinguished by their predicted probability of alcohol, opioid, cannabis, stimulant, and other SUDs. • Classes in which survivors had greater probability of multiple SUDs had greater likelihood of being hospitalized. Background: Substance use is commonly documented among human trafficking (HT) survivors in emergency department (ED) settings. Multiple substance use disorders (poly-SUD) are associated with poor health and psychosocial outcomes. This study identified latent classes and demographic covariates of HT-related ED visits by the types of SUDs documented in survivors’ medical records. Methods: We used cross-sectional data from the United States 2019–2021 Nationwide Emergency Department Sample, including visits of patients aged 12–64 years with an ICD-10-CM code documenting either sex or labor exploitation (N = 4,212). A bias-adjusted three-step latent class analysis was conducted, with SUDs documented via ICD-10-CM codes included as indicators in the model. Results: The optimal three-class solution had superior fit based on pre-selected indicators, low classification error, and acceptable entropy. The largest class comprised 76.01 % of the sample and showed a lower predicted probability of the SUD classes considered. The second largest class (17.27 %) was characterized by high predicted probability of stimulant use disorder with moderately high predicted probability of opioid use disorder. The smallest class (6.72 %) was characterized by high predicted probability of each SUD considered. Class membership was differentially associated with disposition from the ED, nicotine use disorder, and income. Conclusions: Although most ED visits were classified as having relatively low probability of SUD, nearly one quarter of the sample had high risk of either stimulant use disorder or high poly-SUD. Poly-SUD in HT survivors is associated with increased risk of hospitalization. Findings provide direction for tailoring intervention programs to support SUD recovery among HT survivors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.902

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.297
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueAddictive BehaviorsSame topicSubstance Abuse Treatment and OutcomesFrench-language works237,207