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Record W4416377009 · doi:10.47924/neurotarget2025570

Longitudinal Evaluation of Quality of Life in Patients with Deep Brain Stimulation Therapy: Results and Lessons Learned From the Impact of Long Term Interdisciplinary Care in a Single Center

2025· article· W4416377009 on OpenAlexaff
Adriana Lucia López Ríos, Luisa Fernanda Ahunca Velásquez, Carlos Aníbal Restrepo Bravo, William D. Hutchison, Marcia Andrea Cadavid Buitrago

Bibliographic record

VenueNeuroTarget · 2025
Typearticle
Language
FieldMedicine
TopicNeurological disorders and treatments
Canadian institutionsToronto Western HospitalUniversity Health Network
Fundersnot available
KeywordsDeep brain stimulationPsychosocialQuality of life (healthcare)Multidisciplinary approachPsychological interventionIntervention (counseling)RehabilitationOccupational therapy

Abstract

fetched live from OpenAlex

Introduction: This study aims to evaluate the impact of multidisciplinary interventions on the quality of life of 325 patients implanted with deep brain stimulation (DBS) therapy for various diagnoses in our center at Hospital San Vicente Fundacion Rionegro Colombia. Using the validated EQ-5D measurement scale, various dimensions of quality of life were assessed before and after intervention applied in conjuction with a multidisciplinary team with expertice in neurofunctional field.Method: Study Type: Longitudinal, retrospective. Patient Sample: 325 patients implanted with DBS therapy at San Vicente Fundación Hospital in Rionegro, Antioquia. Period of time: Since December 5 2012 to July 30 2025 . Measurement Scale: EQ-5D. Measurement Frequency: Before surgery, 6 months after, and annually thereafter.Discussion: Highly specialized interdisciplinary work enables comprehensive evaluation and treatment of complex neurological conditions, coordinated by a team of experts committed to improving patients' quality of life. Direct collaboration between surgical team and treating specialties was implemented for this sample of 185 patients with different diagnoses, including mainly movement disorders as Parkinson’s disease, essential tremor, dystonia, psychiatrist disorders as severe chronic refractory aggression, osbsessive compulsive disorder, depression, Tourette syndrome, and others as refractory epilepsy and thalamic pain. The program involves specialists from various clinical fields working together for shared and personalized decision-making, including: Neurology, Pain medicine, Neuropsychiatry, Psychiatry, rehabilitation team with physiotherapy, occupational therapy, seepch therapy and others. This neurofunctional care extends beyond the surgical process and works with a psychosocial team supporting patients and families throughout the process, consisting of Neuropsychology, Clinical psychology, Social worker, dietist. We cover in this way the bio psychosocial fields giving to the patients a holistic management and improving the daily activities and the quality of life scores in comparison with same before surgery.Conclusions: The observed improvement in patients can be attributed to a combination of therapeutic interventions and multidisciplinary support. The greatest improvement was seen in patients who adhered to multidisciplinary follow-up and DBS therapy. The study demonstrates that multidisciplinary interventions have a positive impact on patients' quality of life. Further evaluation of these approaches and exploration of new intervention strategies are recommended.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.093
GPT teacher head0.400
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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