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Record W4416397118 · doi:10.1016/j.jcyt.2025.102007

Fate and function of exogenously administered mesenchymal stromal cells: current insights and future directions

2025· article· en· W4416397118 on OpenAlexaff
Ali Shokoohmand, Nikita M. Patel, Lorena R. Braid, Massimo Dominici, Tracy Heng, James A. Ankrum, Jayita Barua, Andrés Caicedo, Michael Creane, Lindsay C. Davies, Claúdia C. dos Santos, Sara Rolandsson Enes, Karen English, Dominique Farge, María Fernández-García, Jacques Galipeau, Nadir Kadri, Maroun Khoury, Stephen Kilfeather, Mauro Krampera, Anna Krasnodembskaya, Manoj M. Lalu, Katarina Le Blanc, Guido Moll, Jan A. Nolta, Cecilia O’Kane, Patrícia R. M. Rocco, Yufang Shi, Daniel J. Weiss, Sowmya Viswanathan

Bibliographic record

VenueCytotherapy · 2025
Typearticle
Languageen
FieldMedicine
TopicMesenchymal stem cell research
Canadian institutionsToronto Rehabilitation InstituteUniversity Health NetworkOttawa HospitalSt. Michael's HospitalSimon Fraser University
Fundersnot available
KeywordsMesenchymal stem cellEfferocytosisStromal cellFunction (biology)Immune systemIn vivoRegenerative medicineApoptosisSystemic administration

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.790
Threshold uncertainty score0.485

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.314
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractno

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