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Record W4416418224 · doi:10.1016/j.clinph.2025.2111444

Hemispheric asymmetry of the ipsilateral silent period following voluntary movement of the opposite hand

2025· article· en· W4416418224 on OpenAlexafffund
Sabira Alibhai-Najarali, John P. de Grosbois, Aaron Emile Philipp-Muller, Jennifer Shao, Matea Skenderija, Jed A. Meltzer

Bibliographic record

VenueClinical Neurophysiology · 2025
Typearticle
Languageen
FieldNeuroscience
TopicHemispheric Asymmetry in Neuroscience
Canadian institutionsUniversity of ReginaBaycrest Hospital
FundersHeart and Stroke Foundation of Canada
KeywordsMotor functionSilent periodDissociation (chemistry)Movement (music)Period (music)Motor areaLaterality

Abstract

fetched live from OpenAlex

OBJECTIVE: To investigate whether post-movement beta rebound (PMBR), a proposed marker of cortical inhibition, reflects interhemispheric inhibition as measured by the ipsilateral silent period (iSP) following voluntary movement and to assess hemispheric asymmetries. METHODS: Twenty right-handed participants underwent transcranial magnetic stimulation (TMS) to elicit iSPs at baseline (no button-press) and eight timepoints following movement of the opposite hand, iSPs and motor-evoked potentials (MEPs) were recorded for both hemispheres. Six participants completed magnetoencephalography (MEG) to characterize beta oscillatory activity during the task. Five participants completed the task without the TMS as a control. RESULTS: iSP magnitude did not significantly change during PMBR period. Instead, post-movement iSP increased in the right hemisphere and decreased in the left, yielding a significant hemispheric difference (p = 0.014). MEG data confirmed symmetrical PMBR across hemispheres. MEPs showed increased excitability post-movement, particularly at early timepoints. Movement alone, without TMS, did not account for hemispheric asymmetry. CONCLUSIONS: PMBR and iSP appear to reflect distinct inhibitory mechanisms. The dissociation suggests PMBR does not index transcallosal inhibition (TCI). Hemispheric asymmetry in iSP suggests stronger TCI following non-dominant hand movements. SIGNIFICANCE: The dissociation between iSP and PMBR underscores the complexity of motor control, informs understanding lateralized motor function and rehabilitation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.320
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes2
Has abstractno

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