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Record W4416500185 · doi:10.1302/1358-992x.2025.14.032

REVISION LUMBAR FUSIONS EXHIBIT WORSE CLINICAL OUTCOMES WHEN COMPARED WITH PRIMARY FUSIONS: A MATCHED COHORT ANALYSIS USING THE CANADIAN SPINE OUTCOMES AND RESEARCH NETWORK REGISTRY

2025· article· en· W4416500185 on OpenAlexaboutno aff
A. Al Duwaisan, Ramtin Hakimjavadi, Tinghua Zhang, Kevin Phan, A. Stratton, Eve C. Tsai, Stephen Kingwell, Eugene K. Wai, Philippe Phan, CSORN Investigators

Bibliographic record

VenueOrthopaedic Proceedings · 2025
Typearticle
Languageen
FieldMedicine
TopicSpine and Intervertebral Disc Pathology
Canadian institutionsnot available
Fundersnot available
KeywordsLumbarConfoundingLumbar spinal stenosisPropensity score matchingConcomitantCohortLumbar spineCohort study

Abstract

fetched live from OpenAlex

The number of patients undergoing lumbar fusion procedures has increased by up to four-fold in the past twenty years.1,2 Revision lumbar fusions may be indicated for a variety of different pathologies including adjacent segment disease, recurrent stenosis or pseudarthrosis. Limited evidence is available regarding patient reported outcomes (PROMs) following revision lumbar fusions, however studies available would suggest worse clinical outcomes following revision lumbar fusions.3 This may confound by a variety of confounders including smoking and pre-operative comorbities.4 The aim of this study was to assess PROMs in patients undergoing revision lumbar fusions when compared to primary lumbar fusions. Patient data was collected from the Canadian Spine Outcomes Research Network database. Patients undergoing lumbar fusions were included. Patients under 18, undergoing surgery for infection, trauma, malignancy, deformity, concomitant cervical or thoracic spine surgery were excluded. Patients undergoing primary vs revision lumbar fusions were matched in a 1:1 ratio using propensity scores. Age, sex, diabetes, smoking status, ASA status and BMI were included in the propensity score model. Mean and standard deviations for ODI, EQ5D, SF-12 PCS, SF-12 MCS, VAS leg and back pain scores preoperatively, 6-18 weeks, 12 months post-operatively were compared using paired t-tests after matching. A total of 1,392 patients were included, with 696 patients in the primary and revision groups each. Patients in both cohorts demonstrated improvement in all PROMs. Patients undergoing revision lumbar fusions however experienced significantly less improvement in all PROMs when compared to their primary fusion counterparts. Despite this, clinical improvement following revision lumbar fusion meet the minimum clinically important difference thresholds for all PROMs. In a matched cohort model, patients undergoing revision lumbar fusions can expect less clinical improvement following surgery when compared to patients undergoing a primary lumbar fusion. They can, however, still obtain clinically meaningful gains following revision fusions. This study represents the largest to date assessing PROMs in patients undergoing revision lumbar fusions. Our results may be of use to spine surgeons counselling patients on expected outcomes following revision lumbar fusions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.993

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.383
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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