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Record W4416504094 · doi:10.1186/s13643-025-02969-y

Neuroimaging in pediatric language development and disorders: a scoping review protocol

2025· article· en· W4416504094 on OpenAlexafffund
Ruochen Ning, Karla N. Washington

Bibliographic record

VenueSystematic Reviews · 2025
Typearticle
Languageen
FieldNeuroscience
TopicNeurobiology of Language and Bilingualism
Canadian institutionsUniversity of Toronto
FundersNational Institute on Deafness and Other Communication DisordersCanadian Institutes of Health ResearchNational Institutes of HealthUniversity of TorontoFoundation for the National Institutes of Health
KeywordsProtocol (science)NeuroimagingLanguage developmentMEDLINEChild development

Abstract

fetched live from OpenAlex

BACKGROUND: Infancy and early childhood represent critical periods for language development, as well as for the diagnosis and intervention of language disorders. Neuroimaging techniques, such as functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI) and magnetoencephalography (MEG), have revolutionized our understanding of the brain's role in language development and disorders. These techniques provide detailed insights into the neural mechanisms underlying language acquisition and the deviations associated with language disorders. However, there is a notable lack of comprehensive literature reviews on the application of neuroimaging techniques in studying pediatric language development and disorders, particularly in children under eight years old in the field of speech-language pathology. This gap in the literature hinders the ability to form a cohesive understanding of the current state of research and its clinical implications, i.e., garnering an understanding of the contributions of these technological tools in understanding language development and disorders. METHODS: To address this gap, we will conduct a scoping review to synthesize literature involving neuroimaging techniques that examines language development and disorders in typically developing children and those diagnosed with language disorders under the age of eight. This review will be guided by the methodological framework proposed by Arksey and O'Malley [18]. A comprehensive and systematic search will be performed across multiple databases (MEDLINE, Embase, EBSCO CINAHL, PsycINFO, SCOPUS, and The Cochrane Library) to identify relevant peer-reviewed publications as well as grey literature. Studies will be screened according to predefined inclusion criteria. Key data from eligible studies will be extracted, synthesized and presented using both quantitative (numerical) and qualitative (narrative) approaches to address the research questions. DISCUSSION: This scoping review aims to provide a comprehensive overview and summary of the methodologies and key findings in neuroimaging studies related to pediatric language development and disorders. The results will identify critical gaps in the current research, highlight the strengths and limitations of various neuroimaging techniques, and suggest future research directions in the field of pediatric neuroimaging for language development. SYSTEMATIC REVIEW REGISTRATION: Open Science Framework (osf.io/5jhk6).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.057
Threshold uncertainty score0.535

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.389
Teacher spread0.343 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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