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Record W4416512879 · doi:10.1371/journal.pgph.0005410

Assessing WHO’s influence: A randomized conjoint experiment on vaccine endorsements in diversified global health systems

2025· article· en· W4416512879 on OpenAlexaboutno aff
Naoko Matsumura, Renu Singh, Christopher Howell, Tobias Heinrich, Matt Motta, Yoshiharu Kobayashi

Bibliographic record

VenuePLOS Global Public Health · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicVaccine Coverage and Hesitancy
Canadian institutionsnot available
FundersKobe University
KeywordsPublic healthGlobal healthConjoint analysisCorporate governanceControl (management)Global governanceHuman health

Abstract

fetched live from OpenAlex

During a novel pandemic, significant uncertainty drives individuals to seek expert guidance on preventive measures such as vaccination. Yet, it remains poorly understood how people process information in a highly complex landscape of global health governance where multiple experts may offer competing, repetitive, or contradictory advice. This study investigates the influence of World Health Organization (WHO)'s endorsements of vaccines amidst this environment. In fall 2020, we conducted a randomized conjoint experiment in Canada (832 respondents, 8,320 profiles evaluated), Japan (1,474, 14,740), and the United States (1,001, 10010), focusing on both whether and when people choose to vaccinate against COVID-19. Our experiment randomly varied exposure to vaccine endorsement information from several prominent global health governance players, including the WHO, the Centers for Disease Control and Prevention (CDC), Oxford University, and the Gates Foundation; and, unlike previous studies, different combinations of these endorsements were used. WHO endorsements increase individuals' willingness to vaccinate more quickly, even when accompanied by endorsements from other credible organizations. However, the effect of WHO endorsements is not significantly stronger than that of other organizations. Notably, the impact of the WHO's endorsement diminishes as the number of endorsements from other organizations increases. The WHO has the greatest impact when it is the first (or among the first) of many organizations to endorse a vaccine as safe and effective, and it may help inspire public confidence in less effective (but potentially lifesaving) vaccines. Overall, our study shows that WHO endorsements significantly reduce vaccine hesitancy, but endorsements from other global actors can exert comparable effects. This highlights that effective global health communication thus depends not on a single authoritative voice but on the timely coordination of multiple credible actors, underscoring the resilience of the global health system in promoting vaccine acceptance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.754
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.402
Teacher spread0.347 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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