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Record W4416537763 · doi:10.1186/s12903-025-07312-4

Success rate of inferior alveolar nerve block in diabetic patients with symptomatic irreversible pulpitis: a prospective study

2025· article· en· W4416537763 on OpenAlexaff
Rakesh Singla, Gurdeep Singh Gill, Namita Jain, Adel S. Alobaid, Suraj Arora, Ahmed Al Malwi, Shan Sainudeen, Priyanka Saluja, Waled Abdulmalek Alanesi

Bibliographic record

VenueBMC Oral Health · 2025
Typearticle
Languageen
FieldDentistry
TopicDental Anxiety and Anesthesia Techniques
Canadian institutionsUniversity of Alberta
FundersDeanship of Scientific Research, King Khalid University
KeywordsInferior alveolar nerveProspective cohort studyClinical trialDiabetes mellitusBlock (permutation group theory)Oral and maxillofacial surgery

Abstract

fetched live from OpenAlex

BACKGROUND: The global prevalence of Diabetes Mellitus is steadily increasing, leading to a larger diabetic population undergoing root canal treatment (RCT). However, clinical studies assessing anesthetic success in diabetic patients are lacking. In diabetic patients, local anesthetic success may be affected owing to neurovasular changes in dental pulps. This study is intended to establish baseline data regarding local anesthetic success in the diabetic population undergoing RCT. The study's main purpose was to assess the success rate of Inferior Alveolar Nerve Block (IANB) in type 2 diabetic patients during RCT of mandibular molars with symptomatic irreversible pulpitis (SIP). METHODS: Sixty-five adult patients diagnosed with SIP in mandibular molars were divided into 2 groups according to their glycated hemoglobin (HbA1c) levels; control group (n = 31, HbA1c < 5.7) and diabetic group (n = 34, HbA1c levels > 6.5). After administering IANB and achieving lip numbness, endodontic access was initiated. Pain was recorded during endodontic procedure using Heft Parker visual analogue scale. Anesthetic success was defined as no or mild pain [score 0-54 mm] throughout endodontic procedure. Chi square test and Mann Whitney U tests were used for statistical analysis. RESULTS: Patients in the diabetic group exhibited significantly higher anesthetic success (94%) as compared to non-diabetic group (74%) (P = 0.016). Patients in the control group were significantly younger than the diabetic group (P < 0.001). Logistic regression revealed that tooth number was significantly associated with anesthetic success while age and gender had no significant influence on anesthetic success. CONCLUSIONS: Within the study limitations, IANB appeared more successful in diabetic patients compared to non-diabetics during RCT of mandibular molars with SIP. Studying local anesthetic success in diabetics is vital for enhancing patient comfort, safety and optimizing outcomes during RCT. TRIAL REGISTRATION: The clinical trial was registered on 24th September 2021 and registration no. is CTRI/2021/09/036813.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.665

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.295
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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