Association of nocturnal intermittent hypoxemia and pulse rate in infants without or with upper airway obstruction
Bibliographic record
Abstract
Oxygen desaturation (≥3%) index(ODI3) values partially overlap in infants without respiratory disorder and those with upper airway obstruction (UAO). We hypothesized that nocturnal intermittent hypoxemia is associated with age-adjusted pulse rate in infants with UAO. <bold>Methods:</bold> Controls (1-12 mo) without respiratory disease had NOx. NOx of infants with UAO were analyzed retrospectively. <italic>Pulse rate index</italic>(PRI)=[(average pulse rate)-(95th percentile value in active sleep for specific age)] X100/(95th percentile value in active sleep) was the outcome; ODI3 and McGill oximetry score (MOS)>1 were explanatory variables. Linear regression/general linear models were used to assess potential association of ODI3 or MOS>1 with PRI and their interaction with study group regarding PRI. <bold>Results:</bold> 138 controls (median age 5.1m [range 1-12.7]) and 23 infants with UAO (2.4m [1.0-11.1]) were included. ODI3 was positively related to PRI in infants with UAO, but not in controls: beta(95%CI) 0.435(0.114-0.755);R<sup>2</sup>=0.275;<italic>P</italic><.010 vs. beta -0.127(-0.463 - 0.209);R<sup>2</sup>=0.004;P<.455. <fig><object-id>erj;66/suppl_69/PA1639/F1</object-id><object-id>F1</object-id><object-id>F1</object-id><graphic></graphic></fig> Interaction of ODI3 with group (UAO vs. controls) regarding PRI was significant (<italic>P</italic>=.023). MOS>1 or its interaction with group was not significant PRI predictor. <bold>Conclusion:</bold> Although ODI3 has lower sensitivity than MOS>1 for UAO (Eur Respir J 2024;64:PA1361), the higher the ODI3 the higher the pulse rate in infants with UAO but not in controls.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".