Association of nocturnal intermittent hypoxemia and pulse rate in infants without or with upper airway obstruction
Bibliographic record
Abstract
Oxygen desaturation (≥3%) index(ODI3) values partially overlap in infants without respiratory disorder and those with upper airway obstruction (UAO). We hypothesized that nocturnal intermittent hypoxemia is associated with age-adjusted pulse rate in infants with UAO. Methods: Controls (1-12 mo) without respiratory disease had NOx. NOx of infants with UAO were analyzed retrospectively. Pulse rate index(PRI)=[(average pulse rate)-(95th percentile value in active sleep for specific age)] X100/(95th percentile value in active sleep) was the outcome; ODI3 and McGill oximetry score (MOS)>1 were explanatory variables. Linear regression/general linear models were used to assess potential association of ODI3 or MOS>1 with PRI and their interaction with study group regarding PRI. Results: 138 controls (median age 5.1m [range 1-12.7]) and 23 infants with UAO (2.4m [1.0-11.1]) were included. ODI3 was positively related to PRI in infants with UAO, but not in controls: beta(95%CI) 0.435(0.114-0.755);R2=0.275;P<.010 vs. beta -0.127(-0.463 - 0.209);R2=0.004;P<.455. erj;66/suppl_69/PA1639/F1 F1 F1 Interaction of ODI3 with group (UAO vs. controls) regarding PRI was significant (P=.023). MOS>1 or its interaction with group was not significant PRI predictor. Conclusion: Although ODI3 has lower sensitivity than MOS>1 for UAO (Eur Respir J 2024;64:PA1361), the higher the ODI3 the higher the pulse rate in infants with UAO but not in controls.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".