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Interstitial lung abnormalities management, a real-life survey of England Targeted Lung Health Check

2025· article· W4416636468 on OpenAlexaff
Laura Fabbri, Richard Hewitt, Brintha Selvarajah, Emily Fraser, Wendy Adams, Haval Balata, Amyn Bhamani, Joe Jacob, Sam M. Janes, Richard W. Lee, Arjun Nair, Emma O’Dowd, Conal Hayton

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Canadian institutionsInstitute of Cancer Research
Fundersnot available
KeywordsInterstitial lung diseaseLungLung cancerHealth careLung functionRespiratory systemHealth professionalsPulmonary function testing

Abstract

fetched live from OpenAlex

Interstitial lung abnormalities (ILAs) are incidental computed tomography (CT) findings affecting more than 5% of the lung parenchyma. Their management remains undefined, raising an emerging challenge in lung cancer screening programmes, such as the UK’s Targeted Lung Health Check (TLHC). This study aimed to assess current ILA management practices through an online survey. Data were collected via Qualtrics, and the survey was distributed via email, social media, and newsletters to healthcare professionals (HCPs) involved in diagnosing or managing interstitial lung disease (ILD) or TLHC referrals. A total of 87 participants completed the survey, including 65.8% respiratory physicians, 15.8% radiologists, 11.7% nurses, and 3.9% general practitioners. Among them, 80.8% worked in centres delivering TLHC. While 50.7% of respondents agreed or strongly agreed that ILAs are clinically important, 19.2% disagreed or strongly disagreed. Moreover, 20.5% strongly disagreed, and 47.9% disagreed that the distinction between ILA and ILD is clear. Amongst HCPs managing ILAs detected through TLHC (n=48), the majority (64.6%) did not follow a standardised management pathway, and 14.6% did not offer routine follow-up for ILA. When offered, follow-up was most commonly every 12 months (58.3%). The majority (70.9%) arranged periodic lung function monitoring; however, 43.8% reported that they did not offer routine CT follow-up. Duration of ILA follow-up was variable, with 35.4% following up for 3 years or less and 35.5% for five years or more. Conclusion: Despite being common incidental findings, ILAs lack a standardised management approach, leading to variability in patient care and services.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.102
Threshold uncertainty score0.203

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.002
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.306
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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