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Is there any relationship between exercise-induced laryngeal obstruction (EILO) and bronchial hyperresponsiveness (BHR) in Norwegian olympic athletes?

2025· article· W4416638678 on OpenAlexaboutno aff
Monica Holmsve, Julie Stang, Hege Clemm, Thomas Halvorsen, Trine Stensrud

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicRespiratory and Cough-Related Research
Canadian institutionsnot available
Fundersnot available
KeywordsBronchial hyperresponsivenessAsthmaProvocation testAthletesNorwegianPopulationLaryngoscopyMethacholine

Abstract

fetched live from OpenAlex

Background: Exercise-induced laryngeal obstruction (EILO) and asthma present with similar symptoms, complicating diagnostic work-up. Bronchial hyperresponsiveness (BHR) is a hallmark of asthma. The relationship between EILO and BHR are therefore important to understand but remain underexplored. Athletes exhibit high rates of both conditions, providing a valuable population for study. Objective: To evaluate the prevalence of EILO in elite athletes and assess the association to BHR. Methods: In this retrospective cross-sectional study, Norwegian athletes participating in the Beijing 2008 summer Olympics (n=80: ♀=62, ♂=18) and in the Vancouver 2010 winter Olympics (n=63: ♀=21, ♂=42), are included. EILO was diagnosed using continuous laryngoscopy during exercise (CLE) or immediate post-exercise bronchoscopy, as feasible during exam. BHR was defined as a positive methacholine provocation test (PD20met≤0.8mg). Results: EILO was identified in 19 (13%) athletes, 13 (9 %) females and 6 (4 %) males. BHR was found in 20 (14%) athletes, with no significant association between EILO and BHR (Phi = -0.021). Co-occurrence of both conditions was found in 3 (2%) athletes, i.e. 16 % of those with EILO also had BHR. However, 8 (42%) athletes with EILO reported using asthma medication. Conclusion: EILO and BHR were both common in athletes but appeared to be unrelated. Notably, a large proportion of athletes with EILO used asthma medications, even in the absence of BHR. Healthcare providers should ensure that respiratory symptoms in athletes are properly evaluated using appropriate diagnostic methods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.333
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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