Cutaneous Small Vessel Vasculitis Associated With Varicella Zoster Infection: A Case Report and Review of the Literature
Bibliographic record
Abstract
Herpes zoster is well-known for its association with large-vessel vasculitis, particularly in the central nervous system. This report highlights a rare diagnosis of small-vessel cutaneous leukocytoclastic vasculitis linked to herpes zoster. A 73-year-old man, during an extended ICU stay following an anterior myocardial infarction complicated by respiratory failure, developed a self-limiting bullous rash. Biopsy revealed epidermal infection by varicella-zoster virus (confirmed through immunohistochemistry and histologic morphology) accompanied by dermal leukocytoclastic vasculitis. This represents the 14th documented diagnosis of small-vessel leukocytoclastic vasculitis associated with varicella-zoster infection. This report broadens the spectrum of herpes zoster presentations, particularly in immunocompromised patients, and provides a valuable reference for clinicians managing atypical manifestations of this infection.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.006 | 0.005 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".