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Record W4416753419 · doi:10.1038/s41598-025-30255-3

Response Inhibition in borderline personality disorder assessed with a gamified stop signal task

2025· article· en· W4416753419 on OpenAlexafffund
Nadine Barakat, Martin Dechant, Emmanuel Poulet, Lionel Cailhol, Jérôme Brunelin, Maximilian A. Friehs, Cécilia Neige

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldPsychology
TopicPersonality Disorders and Psychopathology
Canadian institutionsUniversité de MontréalCentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-MontréalMontreal Council on Foreign RelationsDouglas Mental Health University Institute
FundersFondation Pierre Deniker pour la Recherche et la Prévention en Santé MentaleUniversité de MontréalAgence Nationale de la RechercheFondation Neurodis
KeywordsBorderline personality disorderImpulsivityResponse inhibitionStop signalInhibitory controlCognitionInterpersonal communicationTask (project management)Personality

Abstract

fetched live from OpenAlex

Borderline personality disorder (BPD) is characterized by pervasive difficulties with self-image, interpersonal relationships, emotion regulation and impulse control. Impulsive behaviors can be assessed using tasks such as the stop-signal task (SST). Traditional SSTs are repetitive and cognitively demanding, requiring sustained attention and effort over extended periods. This can be challenging, particularly for clinical populations who often experience difficulties with attention, emotional regulation, and frustration tolerance. In this study, we examined whether a gamified version of the SST (gSST) could effectively differentiate inhibitory control in patients with BPD compared to healthy controls (HC), and explored associations between behavioral performance and self-reported impulsivity. Fifty participants (25 BPD, 25 HC) completed the gSST and the UPPS-P impulsivity questionnaire. Patients with BPD showed significantly faster reaction times, more choice errors, and shorter stop-signal delays, indicating impairments in proactive inhibition. Evidence for reactive inhibition deficits was, however, inconclusive, as no significant group difference emerged for the primary measure, the stop-signal reaction time (SSRT). The SSRT correlated positively with self-reported positive urgency across the sample, suggesting a link between emotionally driven impulsivity and inhibitory control as assessed with a gSST. These findings highlight the potential of gamified cognitive tasks to provide sensitive, engaging, and ecologically valid measures of impulsivity, with implications for both clinical assessment and personalized intervention strategies in BPD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.317
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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