Titagen® for total wellness: results from a randomised, placebo controlled clinical study on adults for osteoarthritis, improvement in skin, nail and health
Bibliographic record
Abstract
Background: Fish collagen has been vital in functional food with natural bioactive compounds to offer potential therapeutic benefits. Titan biotech limited (TBL) has studied Titagen® as a nutraceutical to evaluate improvement in in adults looking to improve skin, hair, nail health and osteoarthritis. Methods: Two randomised, double blinded, placebo controlled clinical studies were conducted on Titagen® of TBL. 48 adults were studied in each of the studies for a period of 90 days. Study 1 (SHN study) was conducted on adults looking to improve skin, hair and nail health with Titagen® dose of 5g per day for 3 months-assessed, using assessments and questionnaire to evaluate skin improvement, hair growth and nail health. Study 2 (OA study) was conducted on adults with osteoarthritis with Titagen® dose of 10 g per day for 3 months-evaluated using assessments and questionnaires. Results: Results showed that Titagen® was better than placebo with statistically significant results in skin health (59.72% vs -51.39), 60 second hair comb test (27.15% vs 2.35%), hair health (18.06% vs -43.06%), nail health (62.50% vs -33.33%), Western Ontario and McMaster universities arthritis index (WOMAC) parameters (39.73% vs 1.72%), pain VAS (70.86% vs 4.21%), quality of life questionnaire (20.83 scores vs 7.31 scores), global impression of change scale results (2.75 vs 4.40). There were no adverse events related to Titagen® and is deemed safe for daily consumption. Conclusions: The clinical studies proved 5 g Titagen® for 90 days improved skin, hair and nail health, 10 g Titagen® for 90 days reduced pain, stiffness in joints and improved quality of life living with osteoarthritis.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.003 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.004 | 0.003 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.009 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".