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Record W4416808757 · doi:10.1111/psyp.70196

Blunted P300 Prospectively Bridges Cognitive Reappraisal and Depressive Symptoms

2025· article· en· W4416808757 on OpenAlexafffund
Kehan Li, Kyle Nash, Yao Zheng

Bibliographic record

VenuePsychophysiology · 2025
Typearticle
Languageen
FieldPsychology
TopicAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Canadian institutionsUniversity of Alberta
FundersNatural Sciences and Engineering Research Council of CanadaChina Scholarship CouncilAlberta InnovatesKillam TrustsUniversity of Alberta
KeywordsCognitive reappraisalCognitionCognitive vulnerabilityModerationContext (archaeology)MediationOddball paradigmDepression (economics)Depressive symptoms

Abstract

fetched live from OpenAlex

Cognitive reappraisal is a crucial modulator of depression. Scant research has examined how the usage of cognitive reappraisal is prospectively linked with depressive symptoms through its modulation effect on P300. Moreover, there is limited knowledge about how the social-environmental context, such as stressful societal disruption, could moderate this prospective process. Adopting a 6-month longitudinal design that recorded both behavioral and electroencephalogram data among 55 young adults (61.8% female) during the COVID-19 pandemic, this study examined the prospective associations from participants' Wave 1 [W1] usage of cognitive reappraisal strategy to W3 depressive symptoms through W2 P300 amplitude during an oddball task, and investigated the potential moderation effect of COVID-19 stress on this mediation path. Cognitive reappraisal was prospectively and indirectly linked to depressive symptoms through reduced P300 amplitude, which was suppressed by COVID-19 stress. Participants with more frequent use of cognitive reappraisal showed blunted P300 amplitude only when COVID-19 stress was low, which was subsequently linked to elevated depressive symptoms. Current findings highlight the central role of reduced P300 as a mediator between cognitive reappraisal and exacerbation of vulnerability for depressive symptoms. Moreover, current findings emphasize the interactive influence between the social-environmental context and cognitive strategy on psychiatric symptoms on a long-term timescale.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.483
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.352
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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