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Record W4416839791 · doi:10.1080/01616412.2025.2597833

Outcomes of mechanical thrombectomy after recent cardiovascular procedures: a multicenter descriptive cohort

2025· article· en· W4416839791 on OpenAlexaff
Sherief Ghozy, Hatem Tolba, Michael Liu, Adam A. Dmytriw, Diego Alejandro Ortega Moreno, Hatim Attar, Muhib Khan, Nicole M. Cancelliere, Ramanathan Kadirvel, Marc A. Lazzaro, Adnan I. Qureshi, Vitor Mendes Pereira, Alejandro A. Rabinstein, David F Kallmes

Bibliographic record

VenueNeurological Research · 2025
Typearticle
Languageen
FieldMedicine
TopicAntiplatelet Therapy and Cardiovascular Diseases
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsProspective cohort studyCohortCohort studyMulticenter studyMEDLINEQuality of life (healthcare)

Abstract

fetched live from OpenAlex

BACKGROUND: Large vessel occlusions (LVOs) in ischemic stroke represent a critical challenge, particularly in the peri-procedural setting of cardiovascular procedures (CVPs). Mechanical thrombectomy (MT) is a well-established treatment for LVOs; however, its outcomes in patients following recent CVPs remain unclear. OBJECTIVE: This multicenter retrospective cohort study aimed to evaluate the outcomes of MT in patients with ischemic stroke occurring within 30 days of CVPs. METHODS: We analyzed data from four centers, including patients aged ≥18 years who underwent MT for LVO within 30 days of CVPs. CVPs included both surgical (e.g. CABG, valve replacement) and minimally invasive procedures (e.g. TAVR, PCI). Baseline characteristics, procedural metrics, and outcomes, including NIHSS and mRS scores, were collected. Statistical analyses were performed using R software. RESULTS: Of 8,947 screened stroke patients, 27 met the inclusion criteria. The median age was 69 years (IQR 60-83), and 56% were male. Anterior circulation occlusions were present in 93% of cases, with a median baseline NIHSS score of 18 (IQR 14-21). Successful reperfusion (TICI ≥2b) was achieved in 85% of cases, with a median of one thrombectomy pass. At 90 days, 30% of patients achieved functional independence (mRS 0-2), while the mortality rate was 44%. Procedural complications were rare (3.7%). CONCLUSION: MT in patients with peri-procedural LVO after CVPs demonstrates success but poor functional recovery compared with baseline. These findings highlight the need for prospective studies to identify patients who may benefit most from MT in this high-risk population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.358
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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