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Record W4416840482 · doi:10.1136/bmjph-2025-003520

Differential impact of the COVID-19 pandemic on chlamydia and gonorrhoea cases among youth and young adults in Canada: an interrupted time series analysis

2025· article· en· W4416840482 on OpenAlexafffundabout
Farhan Khandakar, Nichole Austin, Zihang Lu, Sahar Saeed

Bibliographic record

VenueBMJ Public Health · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicReproductive tract infections research
Canadian institutionsDalhousie UniversityQueen's University
FundersHIV/AIDS and STBBI Research Initiative
KeywordsYoung adultChlamydiaPandemicInterrupted Time Series AnalysisInterrupted time seriesCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreak

Abstract

fetched live from OpenAlex

Introduction: Globally, access to sexual health services declined during the COVID-19 pandemic. In Canada, pre-existing provincial differences in the organisation and delivery of sexual health services may have influenced how the pandemic affected testing and case detection. This study assessed the immediate and sustained impacts of the pandemic on reported chlamydia and gonorrhoea cases among youth and young adults in Ontario and British Columbia. Method: Laboratory-confirmed cases of chlamydia and gonorrhoea among individuals aged under 25 years were analysed using data from provincial surveillance sources from 2016 to 2021. Interrupted time series analyses were conducted using seasonal autoregressive integrated moving average models, stratified by sex and province. Sensitivity analyses examined trends excluding the initial 5 months of the pandemic (March-August 2020) and examined sustained impact through 2023. Results: Following the onset of COVID-19, chlamydia rates declined immediately by 39.13 cases per 100 000 population (95% CI -45.76 to -32.50) in Ontario and by 23.13 per 100 000 (95% CI -27.91 to -18.35) in British Columbia, corresponding to cumulative relative reductions of 42% and 29%, respectively. Gonorrhoea rates decreased by 3.25 per 100 000 (95% CI -4.72 to -1.77) in Ontario and by 1.70 per 100 000 (95% CI -3.92 to 0.51) in British Columbia, translating to cumulative relative reductions of 37% and 22%. Declines in reported cases were more pronounced among females for chlamydia, while males exhibited more sustained decreases over time. Sensitivity analyses confirmed these significant declines after excluding the initial pandemic period and persistent reductions through 2023. Conclusion: Reported chlamydia and gonorrhoea rates among youth and young adults declined substantially during the pandemic, with greater decreases in Ontario than in British Columbia. Sustained reductions suggest ongoing underdiagnosis and underreporting. British Columbia's smaller declines may be partly explained by broader access to their online testing services, GetCheckedOnline.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.916

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.368
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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