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Record W4416855192 · doi:10.1186/s12871-025-03507-y

Neck extension during thyroidectomy: effects on early postoperative cognitive function and optic nerve sheath diameter- a randomized controlled trial

2025· article· en· W4416855192 on OpenAlexaboutno aff
Başak Altıparmak, Ahmet Pınarbaşı, Melike Korkmaz Toker, Ali İhsan Uysal, Mustafa Turan

Bibliographic record

VenueBMC Anesthesiology · 2025
Typearticle
Languageen
FieldMedicine
TopicThyroid and Parathyroid Surgery
Canadian institutionsnot available
Fundersnot available
KeywordsRandomized controlled trialAnesthesiologyClinical trialCognitionEthics committeeNeurology

Abstract

fetched live from OpenAlex

BACKGROUND: During thyroidectomy, patients are commonly positioned with neck extension using a shoulder roll. Excessive extension may impair arterial and venous outflow, compromise cerebral perfusion, and elevate intracranial pressure, potentially leading to postoperative cognitive impairment. This study investigated the effect of shoulder-roll-assisted neck extension on cognitive outcomes and on optic nerve sheath diameter (ONSD). METHODS: After tracheal intubation, patients were randomly assigned to either a shoulder roll group or a control group without a roll. The primary outcome was the Montreal Cognitive Assessment (MoCA) score at 6 h postoperatively. Secondary outcomes included ONSD and the degree of neck extension. RESULTS: Postoperative MoCA scores were significantly lower in the shoulder roll group (20.56 ± 2.71) compared with the control group (23.57 ± 2.37; P < 0.001). ONSD increased over time in both groups (P < 0.001), but repeated-measures analysis showed no significant difference between groups (P = 0.333). Neck extension was greater in the shoulder roll group (126 ± 4.36°) than in the control group (116 ± 3.74°; P < 0.001). CONCLUSIONS: Shoulder roll positioning during thyroidectomy was associated with lower MoCA scores at 6 h, indicating mild postoperative cognitive decline. Although greater neck extension was observed, ONSD values did not significantly differ between groups. TRIAL REGISTRATION: Muğla Sıtkı Koçman University Clinical Research Ethics Committee (approval number T-XII, June 17, 2019). Australian New Zealand Clinical Trials Registry (registration number: ACTRN12619001066178, date of registration: July 31, 2019).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.170
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.258
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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