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Record W4416864642 · doi:10.1162/jocn.a.2414

Lingering Options: How Choice Context Shapes Hippocampal Memory Representations

2025· article· en· W4416864642 on OpenAlexafffund
Azara Lalla, Jamie Snytte, Signy Sheldon

Bibliographic record

VenueJournal of Cognitive Neuroscience · 2025
Typearticle
Languageen
FieldNeuroscience
TopicMemory and Neural Mechanisms
Canadian institutionsMcGill University
FundersCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada
KeywordsSimilarity (geometry)Context (archaeology)Hippocampal formationHippocampusEpisodic memoryNeural correlates of consciousnessRecognition memoryMemoriaRecall

Abstract

fetched live from OpenAlex

There exists a dynamic interplay among the neural mechanisms that underlie decision-making and memory in the brain, with mounting evidence suggesting that the anterior hippocampus plays a role in how we represent past experiences as well as how we engage in choice behavior. A key question, then, is how the anterior hippocampus represents memories of our choices. Prior research has identified conceptual similarity between choice options as a critical factor influencing hippocampal involvement in decision-making. Building on this, we investigated how remembering chosen versus unchosen options from conceptually similar and dissimilar choice scenarios affects hippocampal memory representations. In a preregistered fMRI study, participants made a series of decisions between pairs of food options that were either conceptually similar or dissimilar and then completed an item recognition memory task for the previously presented options. Using representational similarity analysis, we examined hippocampal overlap during recognition among chosen and unchosen options from both similar and dissimilar choice trials. Our key finding was higher anterior but not posterior hippocampal similarity when remembering options from the conceptually similar compared with conceptually dissimilar trials, and further analysis showed that this was not explained simply by concept overlap. Complementary multivariate whole-brain analysis further revealed neural patterns of covariance that distinguished between memory for chosen/unchosen options across the similar and dissimilar trials. Taken together, these findings suggest that the way the brain-particularly the anterior hippocampus-stores and retrieves memories is profoundly impacted by the context in which deliberation occurs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.018
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.990

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.118
GPT teacher head0.374
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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