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Record W4416866468 · doi:10.1007/s12630-025-03040-z

Cardiac risk assessment after noncardiac surgery: a historical cohort study on guideline adherence at a Canadian quaternary care centre

2025· article· en· W4416866468 on OpenAlexaffabout
Constantinos Dean Noutsios, Amanda Marino, Matthew Anacleto-Dabarno, Gabriele Baldini, Amal Bessissow

Bibliographic record

VenueCanadian Journal of Anesthesia/Journal canadien d anesthésie · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac, Anesthesia and Surgical Outcomes
Canadian institutionsMontreal General HospitalMcGill UniversityMcGill University Health Centre
Fundersnot available
KeywordsRisk stratificationCohort studyCohortRisk assessmentGuidelinePrimary careTroponinRetrospective cohort study

Abstract

fetched live from OpenAlex

PURPOSE: Cardiac complications after noncardiac surgery remain a leading source of postoperative morbidity and mortality. In 2016, the Canadian Cardiovascular Society (CCS) published guidelines that outlined an approach to perioperative cardiac risk assessment for noncardiac surgery, integrating biomarkers. We sought to evaluate the adherence to these guidelines at McGill University Health Centre, a quaternary care hospital in Montreal, QC, Canada. METHODS: We conducted a historical cohort study of all patients undergoing elective noncardiac surgery requiring overnight stay between January 2018 and December 2019. The primary outcome was adherence to preoperative B-type natriuretic peptide (BNP) measurement. Secondary outcomes included adherence to postoperative troponin and electrocardiogram (ECG) acquisition, and 30-day postoperative outcomes. RESULTS: Among our cohort of 3,623 patients, BNP measurement adherence was 52.4%. Troponin and ECG acquisition adherence was 34.6% and 30.5%, respectively. Patients with an elevated preoperative BNP had higher incidences of 30-day myocardial injury after noncardiac surgery (20.2% vs 4.3%; P < 0.001), myocardial infarction (5.2% vs 0.5%; P < 0.001), mortality (2.5% vs 0.6%; P < 0.001), and to a lesser extent, cardiac arrest and heart failure decompensation. Patients with elevated postoperative troponin levels had higher incidences of 30-day myocardial infarction (20.7% vs 0.0%; P < 0.001), mortality (7.8% vs 0.6%; P < 0.001), and to a lesser extent, cardiac arrest and heart failure decompensation. Elevated BNP and troponin levels were associated with higher physician follow-up rates. CONCLUSIONS: About half of the patients undergoing noncardiac surgery in our cohort underwent BNP screening as recommended by CCS guidelines; troponin and ECG acquisition adherence was even lower. While postoperative cardiac ischemia is associated with increased 30-day morbidity and mortality, more studies exploring physician risk stratification practice and the impact of increased testing on long-term outcomes are needed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.877
Threshold uncertainty score0.248

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0040.001
Scholarly communication0.0020.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.253
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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