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Record W4416920147 · doi:10.4081/aapm.59

Oral Ialoral<sup>®</sup> Forte <i>versus</i> ultrasound-guided intra-articular cortisone infiltration: results of a retrospective single-center study

2025· article· W4416920147 on OpenAlexaboutno aff
Walter Ciaschi, Fabrizio Fattorini, Pierfrancesco Fusco, Chiara Maggiani

Bibliographic record

VenueAdvances in Anesthesia and Pain Medicine · 2025
Typearticle
Language
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsnot available
Fundersnot available
KeywordsOsteoarthritisAnalgesicTriamcinolone acetonideCorticosteroidRetrospective cohort studyWOMACVisual analogue scalePain relief

Abstract

fetched live from OpenAlex

Osteoarthritis (OA) is a common cause of pain and functional limitation. We compared the analgesic and functional outcomes of Ialoral® Forte, a nutraceutical formulation, with those of ultrasound-guided intra-articular triamcinolone in patients with hip or knee OA and baseline Numeric Rating Scale (NRS) ≤5. This retrospective single-center study included 60 patients (NRS≤5, Kellgren-Lawrence grade I-II) treated between June 2022 and January 2023. Group A received oral Ialoral® Forte (two tablets daily for 40 days); group B underwent two ultrasound-guided intraarticular corticosteroid injections 20 days apart. Pain intensity (NRS) and joint function (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC]) were evaluated at baseline and at 20, 40, 60, and 90 days. Both treatments significantly reduced pain and improved joint function over time. No statistically significant differences were observed between groups (p>0.05). Oral Ialoral® Forte achieved comparable analgesic and functional outcomes to intra-articular corticosteroids, without injection-related risks or contraindications. Oral Ialoral® Forte represents a safe, effective, and non-invasive alternative to intra-articular corticosteroid injections for the management of mild to moderate osteoarthritis, providing similar short-term pain relief and functional recovery with excellent tolerability.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.278
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueAdvances in Anesthesia and Pain Medicine→Same topicOsteoarthritis Treatment and Mechanisms→French-language works237,207→