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Record W4416936739 · doi:10.1093/ehjacc/zuaf140

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2025· article· en· W4416936739 on OpenAlexaff
Pascal Vranckx, D. John Morrow, Sean van Diepen, Frederik H. Verbrugge

Bibliographic record

VenueEuropean Heart Journal Acute Cardiovascular Care · 2025
Typearticle
Languageen
FieldEngineering
TopicMechanical Circulatory Support Devices
Canadian institutionsCanadian VIGOUR CentreUniversity of Alberta
Fundersnot available
KeywordsMEDLINEDiseaseHeart failurePrimary care

Abstract

fetched live from OpenAlex

As the cold December days set in and the Holiday season begins, what better time to settle in with the latest issue of the European Heart Journal—Acute Cardiovascular Care? This December edition brings together an exceptional array of research spanning the full spectrum of acute cardiology and intensive care. With a special focus on thromboembolic disease, it builds on knowledge showcased in previous publications over the last two years,1–8 that have explored right ventricular adaptation, advanced imaging, risk stratification, and mechanical circulatory support in pulmonary embolism. Together, these manuscripts contribute to an evolving picture of how we can continue to refine diagnosis, intervention, and post-acute management to improve outcomes for our most vulnerable patients. Our December Editor’s Choice comes from Monil Majmundar, MD, and colleagues,9 who analysed 14 731 propensity-matched patients from the 2021 National Readmission Database to compare endovascular mechanical thrombectomy (MT) and catheter-directed thrombolysis (CDT) in pulmonary embolism. MT was associated with higher in-hospital mortality (4.4% vs. 3.4%; OR 1.31; 95% CI 1.01–1.68) and major bleeding (6.3% vs. 3.6%; OR 1.79; 95% CI 1.39–2.32), though post-discharge mortality was similar. Notably, high-volume centres demonstrated lower mortality and bleeding rates, narrowing the gap between MT and CDT—underscoring both the crucial role of procedural expertise and institutional experience in interventional PE therapy and the needs for high-quality data from ongoing and future large randomized controlled trials. These real-world insights, accompanied by a probing editorial from Marco Roffi, provide critical context for clinicians navigating this rapidly evolving field.10

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.713
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.244
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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