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Segmentation-Guided Diffusion for Free-Breathing Cardiac Magnetic Resonance Image Restoration

2025· article· en· W4416960486 on OpenAlexaff
Varsha Kesavan, Michelle Noga, Kumaradevan Punithakumar

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicAdvanced MRI Techniques and Applications
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsCardiac magnetic resonanceMagnetic resonance imagingImage qualitySegmentationGold standard (test)Probabilistic logicDiffusionDiffusion-Weighted Magnetic Resonance ImagingMotion (physics)Cardiac magnetic resonance imaging

Abstract

fetched live from OpenAlex

Cardiac magnetic resonance imaging (CMR) is considered the gold standard for assessing cardiac function. However, acquiring high-quality images typically requires patients to hold their breath during scanning. Free-breathing (FB) CMR serves as an alternative for patients who cannot hold their breath; however, it often introduces motion artifacts, degrading image quality and potentially affecting diagnostic accuracy. Although deep generative models have shown promise in correcting motion artifacts, ensuring confidence in the fidelity of reconstructed artifact-free images remains a significant concern. This study quantifies the impact of segmentation masks as guidance in diffusion models to enhance anatomical structure preservation during image-conditioned generation. To that end, a standard diffusion probabilistic model (DDPM) and a segmentation-guided DDPM are trained and evaluated on a public CMR dataset and further applied to restore FB CMR using local hospital data. Quantitative evaluations using signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) over the left and right ventricular regions demonstrate that the segmentation-guided approach produces higher-quality CMR and more accurately preserves anatomical structures compared to the standard DDPM.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.340
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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