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Practical experiments with ultra-low voltage biomedical amplifiers

2025· article· en· W4416963281 on OpenAlexaff
Éric Bharucha, Younès Messaddeq, Benoit Gosselin

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldNeuroscience
TopicNeuroscience and Neural Engineering
Canadian institutionsUniversité Laval
Fundersnot available
KeywordsAmplifierCMOSVoltageNetwork topologyPower (physics)Low voltageTransistor arrayOperational amplifier

Abstract

fetched live from OpenAlex

Low power amplifiers are crucial in many biomedical devices such as muscle signal interfaces and neurological front ends. Furthermore, their importance in analog computing platforms is gaining ground as they provide improved efficiency under increasing demands. As such, reducing amplifier's operational voltage is imperative for low power design. Two topologies were optimized and tested for useful gain at low voltage. A first topology was tested in CMOS and with OTS components, it used body input transconductance. The second, a common source design using an array of MOSFETs that minimized the voltage stack whilst maximizing gain. Both methods provided suitable gain for application in biomedical circuits, and were tested using practical interface biasing. The body amplifier provides useful gain down to 290mV and the CS amplifier provides suitable gain down to 190mV.Clinical and Translational Impact Statement-Low voltage and low power amplifiers reduce risks, as battery longevity is extended. As such, they are a crucial component of medical devices and implants such as heart monitors, pacemakers and health tracking. In addition, these amplifiers are poised to gain importance in biomimetic computing systems based on analog memory.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.273
Threshold uncertainty score0.385

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.337
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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