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Record W4417047947 · doi:10.1016/j.atssr.2025.11.007

Midterm Echocardiographic Outcomes of Minimally Invasive Mitral Valve Surgery in Patients With Previous Cardiac Surgery

2025· article· en· W4417047947 on OpenAlexaffabout
Nicolas Mourad, Durr Al-Hakim, Rosalind Groenewoud, Richard Cook

Bibliographic record

VenueAnnals of Thoracic Surgery Short Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac and Coronary Surgery Techniques
Canadian institutionsVancouver General HospitalUniversity of British Columbia
Fundersnot available
KeywordsCardiac surgeryMitral valve replacementCardiopulmonary bypassPerioperativeMitral regurgitationMinimally invasive cardiac surgeryAortic valve replacementMitral valveMitral valve repair

Abstract

fetched live from OpenAlex

Background: Minimally invasive mitral valve repair (MVr) and mitral valve replacement (MVR) after previous sternotomy are relatively uncommon. This study reports midterm outcomes at a single institution. Methods: All patients with a history of previous cardiac surgery who underwent minimally invasive MVr and MVR with hypothermic fibrillatory arrest at our institution (Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada) between 2006 and 2024 were included. Follow-up echocardiographic reports were reviewed at 1 year, 1 to 3 years, 3 to 5 years, and 5+ years. Primary outcomes included postoperative complications, all-cause mortality, and rates of grade 3 to 4 mitral regurgitation at follow-up. Results: A total of 31 patients met the inclusion criteria (25.8% female patients), and their median age was 64 years. A total of 18 patients underwent MVR, and 13 underwent MVr. The most common previous cardiac operations were aortic valve replacement (AVR), coronary artery bypass graft, and MVR. All redo procedures were completed using hypothermic fibrillatory arrest (mean, 23.3 [2.5] °C; median duration, 143.0 minutes [interquartile range, 110.5-175.0 minutes]) for myocardial protection. The 30-day, 5-year, and 10-year all-cause mean mortality rates were 0.0% (0.0%), 12.9% (6.0%), and 25.8% (7.9%), respectively. Patients with previous AVR with or without ascending aortic replacement represented 50% of total deaths. Overall, 4 (12.9%) patients had recurrent grade 3 to 4 mitral regurgitation: 3 died, and 1 had subsequent double-redo MVR. Conclusions: Our study demonstrates low perioperative mortality rates, thus implying the safety of fibrillatory arrest for myocardial protection in redo minimally invasive MVr and MVR. We also identified that patients with AVR with or without ascending aortic replacement face a higher midterm risk, given the technical difficulty of operating with fibrillatory arrest on the anterolateral portion of the mitral valve when the aortic annulus or root is inflexible.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.119
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.007
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.317
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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