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Record W4417077494 · doi:10.1186/s12889-025-25819-x

Life meaning and purpose as an unrecognized determinant of mental health equity in Canadian adolescents

2025· article· en· W4417077494 on OpenAlexafffundabout
Valerie Michaelson, William Pickett, Nathan King, Pauli Gardner, Mark A. Ferro, Mary Jean Costello, Scott T. Leatherdale, Karen A. Patte

Bibliographic record

VenueBMC Public Health · 2025
Typearticle
Languageen
FieldPsychology
TopicPsychological Well-being and Life Satisfaction
Canadian institutionsUniversity of WaterlooQueen's UniversityHomewood Research InstituteBrock University
FundersCanadian Institutes of Health ResearchHealth CanadaCanada Research Chairs
KeywordsMental healthMeaning (existential)Public healthBiostatisticsEquity (law)Life course approachEpidemiologyHealth equity

Abstract

fetched live from OpenAlex

BACKGROUND: The etiological pathways through which structural determinants result in health inequities remain unclear. In adolescent populations, a sense of meaning and purpose in life has been hypothesized and considered cross-sectionally to represent an intermediary determinant in the pathway that connects wealth with mental health outcomes. The purpose of this study was to prospectively explore how life meaning and purpose contributes to disparities in mental health observed by affluence in an adolescent cohort. METHODS: We used two-year linked survey data collected from a cohort of 17,745 students at Canadian secondary schools in 2020/2021 and 2021/2022. Structural equation models were used to examine the prospective associations between students' perceived relative family affluence and anxiety and depression symptoms, mediated by their sense of meaning and purpose in their lives. Models were stratified by gender identity. RESULTS: The prevalence of clinically-relevant depression and anxiety symptoms was lowest among cisgender boys and highest among transgender and gender diverse adolescents. Conversely, life meaning and purpose was reported most often by cisgender boys, followed by cisgender girls. Meaning and purpose in life partially mediated associations between relative affluence and depression and anxiety symptoms. CONCLUSION: Consistent with determinants of health models and past cross-national analyses of adolescent health survey data in Canada, results provide prospective evidence in support of life meaning and purpose as an intermediary determinant of mental health in adolescents. Experiences that foster a sense of meaning and purpose in life require recognition as determinants of health, and suggest an intangible resource that can be applied to clinical and public health initiatives that address adolescent mental health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.027
Threshold uncertainty score0.197

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.002
Science and technology studies0.0040.002
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.080
GPT teacher head0.433
Teacher spread0.353 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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