Meta-analysis of preoperative CALLY index for predicting the prognosis of cancer
Bibliographic record
Abstract
OBJECTIVE: This study aims to evaluate the predictive value of the CALLY index in cancer prognosis via systematic review and meta-analysis. METHODS: PubMed, Web of Science, Embase, and Cochrane were searched up to November 2024. Study quality was evaluated using the Newcastle-Ottawa Scale (NOS), and meta-analysis was performed with STATA 17.0. RESULTS: Among 21 cohort studies,the findings indicated that, regarding overall survival (OS), a low CALLY index was correlated with a 113% elevated likelihood of all-cause mortality compared to those with a higher CALLY index (risk ratio [RR] = 0.47, 95% confidence intervals [95%CI]: 0.42-0.53). An 85% elevated risk of disease-free survival (DFS) and relapse-free survival (RFS) was observed in individuals with a low CALLY index (pooled RR = 0.54, 95%CI: 0.46-0.63). Moreover, a lower CALLY index was correlated with a significantly greater tumor burden (standardized mean difference (SMD) = -0.64, 95%CI: -0.76-0.52). The stage-specific analysis demonstrated that a low CALLY index significantly increased the risk of cancer progression by 54% in individuals at stage II (RR = 0.65, 95%CI: 0.43-0.98) and by 67% in individuals at stage III (RR = 0.60, 95%CI: 0.43-0.86). CONCLUSION: The CALLY index independently predicts adverse cancer outcomes.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.001 | 0.003 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".