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Record W4417131323 · doi:10.1007/s11606-025-10053-3

Preparing to Meet the Needs of a Growing Older Adult Population with Type 1 Diabetes: A Narrative Review

2025· article· en· W4417131323 on OpenAlexaff
Anna R. Kahkoska, Joshua J. Neumiller, Anastasia-Stefania Alexopoulos, Antoine Christiaens, Tali Cukierman‐Yaffe, Nicole Ehrhardt, Elbert S. Huang, Thaer Idrees, Lori M. Laffel, Sei J. Lee, Naushira Pandya, Richard E. Pratley, Leocadio Rodríguez‐Mañas, Christine Slyne, Elena Toschi, Ruth S. Weinstock, Adriana Wisniewski, Carol Wysham, Medha Munshi

Bibliographic record

VenueJournal of General Internal Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicDiabetes Management and Research
Canadian institutionsInstitute of Nutrition, Metabolism and Diabetes
FundersDuke Clinical Research InstituteNational Institute of Child Health and Human DevelopmentFonds De La Recherche Scientifique - FNRSACCP FoundationJuvenile Diabetes Research Foundation United States of AmericaFoundation for the National Institutes of HealthNational Science Foundation
KeywordsHypoglycemiaType 1 diabetesPopulationNarrative reviewDiseaseMEDLINEType 2 Diabetes MellitusDiabetes mellitusHealth care

Abstract

fetched live from OpenAlex

The prevalence of diabetes is rising among older adults. While most diabetes cases in older adults are type 2 diabetes mellitus (T2D), advances in type 1 diabetes mellitus (T1D) management and rising rates of adult-onset T1D have translated into a growing number of individuals with T1D living into older adulthood. This narrative review integrates existing evidence on management of T1D in older adults with expert opinions to provide practical guidance for generalists increasingly encountering the unique challenges and complexities of this growing population. The profound heterogeneity in clinical presentation, pathobiology, and disease progression across the older adult population can make it challenging to differentiate older adults with T1D from those with insulin treated T2D, particularly in adult-onset cases. However, timely diagnosis is critical to minimize exposure to hyperglycemia and reduce the risk for complications, as individuals with T1D rely entirely on exogenous insulin and require intensive self-management to prevent acute complications like hypoglycemia and ketoacidosis. Self-management of T1D in older adults presents unique challenges, including a high risk of hypoglycemia that must be mitigated in the setting of a lifelong requirement for insulin and evolving mismatches between intensive self-management demands and an older person's capacity for self-care. The growing number of older adults with T1D underscores a lack of access to specialized care and limited training and resources for evidence-based management in primary care and post-acute/long-term care settings, as well as the dearth of high-quality clinical evidence specific to this population to inform care. Research to support changes across healthcare systems and at the policy level, in combination with education and multi-specialty collaboration, will ensure that healthcare providers and health systems are equipped and prepared to better meet the needs of the growing population of older adults with T1D.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.021
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.021
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0030.003
Open science0.0010.002
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.345
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractno

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