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Record W4417138045 · doi:10.1055/a-2668-0824

Core GRADE for evidence syntheses

2025· article· de· W4417138045 on OpenAlexaboutno aff
Tobias Braun

Bibliographic record

Venuephysioscience · 2025
Typearticle
Languagede
FieldComputer Science
TopicAI-based Problem Solving and Planning
Canadian institutionsnot available
Fundersnot available
KeywordsCertaintyContext (archaeology)Strengths and weaknessesCore (optical fiber)Quality (philosophy)Clinical PracticeSystematic error

Abstract

fetched live from OpenAlex

GRADE is a globally recognized approach for assessing the certainty of evidence (also: quality or certainty of evidence) and formulating recommendations in systematic reviews, guidelines and other evidence syntheses. GRADE (Grading of Recommendations Assessment, Development and Evaluation) was introduced approximately 20 years ago by an international working group led by Canadian physician Gordon Guyatt, one of the pioneers of evidence-based practice [ 1 ]. GRADE has evolved continuously over time and has now reached a high level of complexity. In the context of the strengths and weaknesses of the established GRADE concept, the Core GRADE approach recently presented by Guyatt et al. represents a significant development, which should lead to simpler and more frequent use of GRADE [ 2 ]. The new Core GRADE approach is described in detail in a 7-part series of articles and is highly relevant to physiotherapy science [ 2 ]. Publication History Article published online: 08 December 2025 © 2025. Thieme. All rights reserved. Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.114
metaresearch head score (Gemma)0.500
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.886
Threshold uncertainty score0.605

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1140.500
Meta-epidemiology (narrow)0.0040.003
Meta-epidemiology (broad)0.0150.021
Bibliometrics0.0510.028
Science and technology studies0.0030.005
Scholarly communication0.0140.007
Open science0.0130.008
Research integrity0.0100.013
Insufficient payload (model declined to judge)0.1470.041

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.162
GPT teacher head0.356
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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