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Record W4417165657 · doi:10.1093/jsxmed/qdaf320.121

(121) Short Term Results and Safety Profile of Hyaluronic Acid Penile Girth Enhancement Using the PhalloFill Standardized Technique Procedure: Comparable Outcomes for Both Circumcised and Uncircumcised Men

2025· article· en· W4417165657 on OpenAlexaffabout
Adel Arezki, Iman Sadri, David Bouhadana, Kevin C. Zorn

Bibliographic record

VenueThe Journal of Sexual Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicSexual function and dysfunction studies
Canadian institutionsMcGill University
Fundersnot available
KeywordsErectile dysfunctionBody mass indexGirth (graph theory)DemographicsRetrospective cohort studyPeyronie's diseaseComplication

Abstract

fetched live from OpenAlex

Abstract Introduction Penile girth enhancement (PGE) procedures have increasingly been sought after for aesthetic and functional reasons for the care of penile dysmorphia disorder (PDD). Unlike other HA injection techniques with variable chain length, cross-linking, chemical modifications and external pH which that affect its structure and viscosity, the standardized PhalloFill technique and unique sleeve system offers security and reproducibility of outcomes with more even distribution and prevention of unwanted migration. Objective This study provides a retrospective review of an HA-based penile girth enhancement focusing on treatment outcomes and complication rates. Methods Data was retrospectively collected for 59 men who underwent HA-based dermal filler at BPH Canada Male Sexual Wellness Center, Montreal, Canada, from November 2023 to October 2024. Baseline demographics and clinical characteristics were recorded, including age, circumcision status, body mass index (BMI), and prior medical history such as erectile dysfunction and previous treatments. Preoperative measurements of mid, base, and apex penile girth were obtained, with patients receiving between 4 to 6 units of HA filler. Complications were tracked, and changes in penile measurements were assessed at 1-month post-procedure. Results The mean age of treated men was 44.2 years (SD 10.5), with a mean BMI of 26.6 (SD 7.4). Baseline penile dimensions were mean base-to-corona length 3.87” (range 2.24-5.4”), and mean girth at mid -phallus was 3.64” (range 2.5-4.5”). Men with circumcision and active smoking were observed in 49% and 37%, respectively. Initial treatments were 61%, 5% and of 34% of men were injected with 4,5 an6 units of HA filler. All men demonstrated significant mid-girth enhancement from baseline to 1 month, with a mean increase of 0.36 “ (SD 0.16, p < 0.01). There were no difference between girth enhancement between circumcised and non-circumcised mean (0.35”vs 0.36” respectively). Changes from baseline in apex and base girth were observed at 0.34 “ (SD 0.35, p = 0.56) and 0.31”(SD 0.28, p = 0.154), respectively. Overall complication rates were low, with mild skin erythema reported in 6 men (edge of sleeve treated with Polysporin) and 7.3% filler. All complications resolved with conservative management, and no long-term sequelae were observed. No Clavien-Dindo Grade >2 were observed. No injection-related infections, abscess, pain or hospitalization/ER visit was reported. No patient required dissolution hyaluronidase treatments. Conclusions Phallofill HA dermal filler with standardized treatment protocol using its unique penile compression sleeve for PGE is associated with significant, consistent girth gains across circumcised and uncircumcised men, with a low incidence of complications. Further studies are ongoing to assess subsequent treatments in girth gains and HA girth durability. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Procept, Boston Scientific, Laborie, Olympus, Zenflow

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.624
Threshold uncertainty score0.472

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.349
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes2
Has abstractyes

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