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Record W4417222671 · doi:10.1186/s43045-025-00605-y

Evaluation of anxiety and depression among patients recovered from acute kidney injury

2025· article· en· W4417222671 on OpenAlexaboutno aff
Yasser M. Mostafa, Rehab Elsayed Abd Elmonem, Mohamed Elwasify, Ahmed A. Eldeeb

Bibliographic record

VenueMiddle East Current Psychiatry · 2025
Typearticle
Languageen
FieldMedicine
TopicAcute Kidney Injury Research
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentAnxietyDepression (economics)DialysisHamilton Anxiety Rating ScaleQuality of life (healthcare)Acute kidney injuryProspective cohort study

Abstract

fetched live from OpenAlex

Abstract Background Acute kidney injury (AKI) is a common clinical condition with high morbidity and mortality. This research aims to assess depression, anxiety, cognitive function, and quality of life (QoL) in patients recovered from AKI and examine their association with recovery status and clinical outcomes. Methods This prospective cohort study included 53 AKI patients and 53 age- and sex-matched healthy controls. Psychiatric assessments included the Hamilton Anxiety Rating Scale (HARS), Hamilton Depression Rating Scale (HAM-D), and Generalized Anxiety Disorder-7 (GAD-7). Cognitive function was evaluated using the Montreal Cognitive Assessment (MoCA), and health-related QoL with the SF-36 questionnaire. Assessments were performed at baseline, 3, and 6 months. Results AKI patients demonstrated significantly elevated HARS, HAM-D, and GAD-7 scores than controls at baseline, 3, and 6 months (all p < 0.001), with progressive worsening during follow-up. QoL scores were significantly diminished in AKI patients as opposed to controls at all time points (baseline: 61.6 ± 6.2 vs. 72.7 ± 8.5; 6 months: 48.3 ± 5.3 vs. 77.4 ± 6.7; p < 0.001). MoCA scores were also reduced in AKI patients (19.1 ± 3.8 vs. 21.1 ± 4.0; p = 0.013). Anxiety and depression correlated with ICU stay, number of dialysis sessions, and serum creatinine, while QoL inversely correlated with age ( r =-0.40, p = 0.003). Patients with incomplete recovery or dialysis dependence had significantly elevated anxiety and depression scores. Conclusions AKI survivors experience persistent psychological distress, cognitive impairment, and reduced QoL, particularly in those with incomplete renal recovery. Early psychiatric assessment and targeted interventions should be integrated into post-AKI care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.171
Threshold uncertainty score0.795

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.335
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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