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Evaluation of Behavioral Changes and Immunoglobulin Levels in Dogs with Parvoviral Enteritis Treated with Different Antibacterials

2025· article· en· W4417235973 on OpenAlex
Cenk Er, Muhammed Hanifi Selvi, Ömer Barış İnce

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueEgyptian Journal of Veterinary Science · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Virus Infections Studies
Canadian institutionsnot available
Fundersnot available
KeywordsEnteritisAntibodyImmune systemAntibioticsDiarrheaVomitingImmune status

Abstract

fetched live from OpenAlex

Canine parvoviral enteritis (CPE) is a highly contagious and often fatal viral disease that primarily affects puppies, leading to severe gastrointestinal symptoms and immune suppression. This study aimed to evaluate both immunological and behavioral changes in dogs diagnosed with parvoviral enteritis and treated with different antibacterial agents. A total of 34 puppies presenting with clinical signs such as hypothermia (n=24), hyperthermia (n=4), dehydration (n=30), vomiting (n=32), and diarrhea (n=14; 12 of which were hemorrhagic) were included in the study. Immunoglobulin A (IgA) and immunoglobulin G (IgG) levels were measured and compared with healthy controls. Average IgA and IgG levels were lower than those of the control group and did not reach normal values throughout the study period. Behavioral assessments revealed that loss of appetite, dehydration, and exhaustion were observed in all dogs. Snarling, moaning, discontent, and drowsiness behaviors were analyzed according to breed, age, gender, and treatment groups. While snarling, discontent, and drowsiness showed no significant differences between groups (p>0.05), a statistically significant difference was found in moaning and discontent behaviors according to treatment groups (p<0.05). Females were generally more prone to display behavioral changes, and recovery was observed earlier in males. Among breeds, Pinschers showed more snarling and Labrador Retrievers exhibited more moaning and discontent behaviors. The study suggests that antibacterial treatments, while not significantly altering immunoglobulin levels, may influence behavioral responses during the recovery process of dogs with parvoviral enteritis. These findings highlight the importance of monitoring both immune and behavioral parameters in the management of CPV infection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.815
Threshold uncertainty score0.177

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.085
GPT teacher head0.324
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it