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Record W4417259442 · doi:10.1038/s41598-025-32227-z

A novel cryptographic framework and mathematical modeling for secure transmission of Parkinson’s disease data using RSA and block-based secret sharing

2025· article· en· W4417259442 on OpenAlexaff
Thalapathiraj Sambandham, H. M. Srivastava, Stalin Thangamani, Majeed A. Yousif, Abdelhamid Mohammed Djaouti, Pshtiwan Othman Mohammed

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldComputer Science
TopicChaos-based Image/Signal Encryption
Canadian institutionsUniversity of Victoria
FundersKing Faisal University
KeywordsEncryptionRobustness (evolution)CryptographySecret sharingSecure multi-party computationKey (lock)Mathematical proofCryptographic primitive

Abstract

fetched live from OpenAlex

The secure transmission of medical data is an essential requirement in modern telemedicine systems, particularly for chronic neurological disorders such as Parkinson's disease. This paper proposes a novel hybrid cryptographic framework that combines RSA encryption with block-based secret sharing enhanced by a Hilbert matrix-driven mathematical model. The framework introduces dynamic block-wise key generation and adaptive sharing to strengthen data confidentiality and robustness against cryptanalytic attacks. Mathematical modeling is employed to analyze encryption stability, numerical conditioning of the Hilbert matrix, and the diffusion properties of the key space. The proposed method is validated using publicly available Parkinson's EEG and spiral drawing datasets, with quantitative analysis including encryption/decryption time, computational overhead, and image quality metrics (PSNR, SSIM). The framework is further benchmarked against AES-Shamir and ECC-based hybrid models. Experimental results indicate that the proposed system achieves higher security entropy and lower computational cost, making it suitable for deployment in resource-constrained medical IoT environments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.303
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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