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Record W4417281018 · doi:10.1016/j.inat.2025.102162

Successive thoracic anterolateral intervertebral disc herniations with ossification-fusion: a cadaveric case analysis with MRI and clinical review

2025· article· en· W4417281018 on OpenAlexaff
Logan D. Tlam, Joseph X. Anders, Maggie Minett, Chad J. Hungerford, Ethan L. Snow

Bibliographic record

VenueInterdisciplinary Neurosurgery · 2025
Typearticle
Languageen
FieldMedicine
TopicSpine and Intervertebral Disc Pathology
Canadian institutionsCanadian Chiropractic Association
Fundersnot available
KeywordsCadaveric spasmIntervertebral discAnterior longitudinal ligamentMagnetic resonance imagingPosterior longitudinal ligamentLumbarIntervertebral diskLigamentVertebral column

Abstract

fetched live from OpenAlex

Background Intervertebral discs (IVDs) permit resilient deformability and shock absorption between vertebrae. IVD herniation from damage or disease most commonly occurs in the lumbar and cervical spines, in the posterolateral direction, and to a single IVD. This investigation seeks to examine a unique case of successive thoracic anterolateral IVD herniations with gross and magnetic resonance imaging (MRI) analyses and present the case with a literature-based clinical narrative. Methods The case was discovered in an adult human cadaver. T1-weighted MRI was performed on the implicated spine, and serial cross-sectioning was completed through each IVD. The herniations were photographed at each stage, and linear parameters of the spinal pathologies were measured. Results The ossified herniations extruded 11.1 ± 2.1 mm from the typical IVD border, and the ossified bridging over the vertebral bodies extruded 6.9 ± 2.6 mm from the typical vertebral body border. The extrusions displaced the functionality of the anterior longitudinal ligament 7.37 mm left of midline, and comparison of gross in situ and cross-sectional imaging with MRI illustrated the extent of IVD herniation and vertebral fusion in the clinical perspective. Conclusions The present cadaveric case involving multiple uncommon features of IVD herniation accompanied by MRI and clinical narrative may enhance clinical awareness among spine specialists, particularly in recognizing uncommon presentations of thoracic IVD ossification and vertebral hyperostosis. This report may also serve as a valuable reference for to clinical anatomists, Doctors of Chiropractic Medicine, spine neurosurgeons, and other healthcare experts when discussing or treating related patient cases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.995

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.386
Teacher spread0.366 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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