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Record W4417304731 · doi:10.1002/mdc3.70305

<scp>MDS PD</scp> e‐Diary: A New Patient‐Centered Digital Tool in Development for People with Parkinson's Disease

2025· article· en· W4417304731 on OpenAlexafffund
Pablo Rábano‐Suárez, Mariana H.G. Monje, Joaquín A. Vizcarra, Serene S. Paul, Sabela Avión, Michael A. Morse, Matěj Škorvánek, Michelle Hyczy de Siqueira Tosin, Rebecca Fuller, Travis H. Turner, Marieke C. J. Dekker, Deborah A. Hall, K. J. Bergmann, Jesse M. Cedarbaum, Walter Maetzler, Alberto J. Espay, Pablo Martínez‐Martín, Glenn T. Stebbins, Tiago Mestre, Álvaro Sánchez‐Ferro

Bibliographic record

VenueMovement Disorders Clinical Practice · 2025
Typearticle
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsUniversity of OttawaCentre for Movement DisordersCancer Care Nova Scotia
FundersFeinberg School of MedicineNational Institutes of HealthCanadian Institutes of Health ResearchIpsenPerelman School of Medicine, University of PennsylvaniaMitsubishi Tanabe Pharma CorporationParkinson CanadaMichael J. Fox Foundation for Parkinson's ResearchBoston Scientific CorporationEVER Neuro PharmaPhysiotherapy Research FoundationAgentúra na Podporu Výskumu a VývojaFondation Brain CanadaEuropean CommissionMarcus FoundationAcorda TherapeuticsUniversity of OttawaU.S. Department of Veterans AffairsRush UniversityUniversity of CambridgeBiogenNorthwestern UniversityPhysicians' Services Incorporated FoundationUniversity of PennsylvaniaTeva Pharmaceutical IndustriesWounds AustraliaInternational Parkinson and Movement Disorder SocietyCHDI Foundation
KeywordsDiseaseMEDLINEDigital healthResearch development

Abstract

fetched live from OpenAlex

BACKGROUND: There is a need to better evaluate Parkinson's disease (PD) impact on daily lives of People with Parkinson's (PwP). OBJECTIVES: To conceptualize a novel digital tool, the MDS PD e-Diary that has been commissioned by the International Parkinson's disease and Movement Disorders Society. METHODS: Using a modified Delphi methodology, we sought consensus among key stakeholders (PwP, care partners, PD specialists, industry, regulatory representatives) through online questionnaires, focus groups, and a broad community survey. RESULTS: The consensus resulted in a multiplatform patient-reported outcome tool to track PD progression. It includes an Item Bank of symptoms and activities featuring two interconnected user modes. The personal mode is a customizable self-tracking tool that allows data sharing with professionals to improve standard care. The research mode employs a predefined responsive item to enhance research and clinical trials. CONCLUSION: The MDS PD e-Diary was designed to capture PD progression and its impact on PwP lives, potentially transforming research and clinical practice. Its further development and validation processes are underway.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.654
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.321
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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