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Record W4417360709 · doi:10.5489/cuaj.9368

A systematic appraisal of emerging alternative therapies in men’s health and wellness

2025· review· en· W4417360709 on OpenAlexaffvenue
Yazan Qaoud, Maya Morcos, Ahmed Shoeib, Yara Qureshi, Matthew Mak, Amanda Ross, Humberto Vigil, Luke Witherspoon

Bibliographic record

VenueCanadian Urological Association Journal · 2025
Typereview
Languageen
FieldMedicine
TopicComplementary and Alternative Medicine Studies
Canadian institutionsUniversity of OttawaOttawa Hospital
Fundersnot available
KeywordsSample (material)Alternative medicineMEDLINESystematic reviewClinical trialPublic health

Abstract

fetched live from OpenAlex

INTRODUCTION: The use of alternative therapies for men's health continues to grow in popularity, as claims of their urologic and overall health benefits become more widespread. This study aimed to evaluate commonly purported therapies (intravenous [IV] nutrient infusions, saunas, ice baths, light therapy, and condensed nutritional supplements) in the treatment or improvement of men's urologic health. METHODS: A scoping review was conducted using the databases PubMED and SCOPUS to identify literature discussing each intervention. Outcomes of interest were urologic parameters in men aged 18 and above. RESULTS: Overall, the results were often conflicting or inconclusive. IV therapy lacked any supportive evidence for the claims regarding its benefits in erectile dysfunction, sperm quality, or testosterone enhancement. Sauna had mixed outcomes, with some temporary increases in testosterone and reversible adverse effects on sperm parameters. Similarly, cold water immersion showed inconsistent benefits for testosterone, with improvements in fatigue and soreness. Light therapy showed non-significant changes in hormone levels, while improvements in sexual satisfaction and hair regrowth were noted. While some herbal products showed benefits for sexual function, testosterone levels, and sperm quality, others had negligible or inconsistent outcomes. CONCLUSIONS: There is a discordance between media claims and scientific literature regarding the impact of alternative therapies for men's health. This data is significantly limited by small sample sizes and a lack of long-term followup. There is a need for larger-scale trials to better inform patient counseling.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.027
metaresearch head score (Gemma)0.087
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.027
Threshold uncertainty score0.144

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0270.087
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0070.007
Bibliometrics0.0160.012
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.365
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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Same venueCanadian Urological Association JournalSame topicComplementary and Alternative Medicine StudiesFrench-language works237,207