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Record W4417361046 · doi:10.1097/brs.0000000000005602

Saving Fusion Levels in Lenke 1/2 AR Curves

2025· article· en· W4417361046 on OpenAlexaff
Michael W. Brown, Arun R. Hariharan, Tracey L. Bryan, David S. Feldman, Craig R. Louer, John S. Vorhies, Joshua Murphy, Keith Bachmann, Robert H. Cho, Peter G. Gabos, Amit Jain, Baron S. Lonner, Firoz Miyanji, Amer F. Samdani, Suken A. Shah, Michael P. Kelly, Peter O. Newton

Bibliographic record

VenueSpine · 2025
Typearticle
Languageen
FieldComputer Science
TopicCryptography and Residue Arithmetic
Canadian institutionsBC Children's Hospital
Fundersnot available
KeywordsRadiographyVertebraRetrospective cohort studyLumbarMultivariate analysisSpinal fusionScoliosisIdiopathic scoliosis

Abstract

fetched live from OpenAlex

STUDY DESIGN: Retrospective cohort from a multicenter registry. OBJECTIVE: Characterize the variability of the last substantially touched vertebra (LSTV) in Lenke 1- and 2-AR curves and evaluate whether clinical or radiographic factors permit fusion short of the LSTV without increased adding-on risk. SUMMARY OF BACKGROUND DATA: Lenke 1 and 2A curves with an R modifier based on L4 tilt in adolescent idiopathic scoliosis (AIS) are associated with a higher risk of adding-on after posterior spinal fusion (PSF). Fusion to the LSTV may reduce this risk but often requires extending into the distal lumbar spine, compromising motion. The safety of terminating fusion proximal to the LSTV in select patients, without increasing adding-on risk, remains uncertain. METHODS: Patients with Lenke 1- or 2-AR curves undergoing PSF with minimum 2-year follow-up were identified. Radiographs were reviewed to determine LSTV level and assess for adding-on. Patients were stratified based on whether the lowest instrumented vertebra (LIV) was proximal to or at the level of/distal to the LSTV. Among those fused proximal, univariate and multivariate analyses were used to identify protective factors. Subgroup analyses were performed by LSTV level. RESULTS: Of 324 patients, 144 (44.4%) were instrumented proximal to the LSTV. Adding-on occurred in 16.0% of all patients, more frequently in short fusions (21.5% vs. 11.7%, P=0.016). Multivariate analysis identified higher Risser (OR=1.62, P=0.006) and greater main thoracic correction (OR=1.09, P<0.001) as protective. Adding-on was rare (4.0%) when the LSTV was L4, even when fused short. CONCLUSIONS: In skeletally mature patients with adequate thoracic correction, fusion proximal to the LSTV in Lenke 1- and 2-AR curves may be performed safely. When the LSTV is L4, fusion to that level may be unnecessary, offering an opportunity for lumbar motion preservation without increased risk of adding-on. LEVEL OF EVIDENCE: IV.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.934
Threshold uncertainty score0.232

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.266
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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