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Record W4417364375 · doi:10.25258/ijpqa.16.10.55

Comparison of Early Versus Delayed Physiotherapy in Patients Undergoing Total Knee Replacement: An Observational Study

2025· article· W4417364375 on OpenAlexaboutno aff
Yogeshkumar Gadhavi, Tarun Dodiya

Bibliographic record

VenueInternational Journal of Pharmaceutical Quality Assurance · 2025
Typearticle
Language
FieldMedicine
TopicTotal Knee Arthroplasty Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsObservational studyWOMACRandomized controlled trialVisual analogue scaleOsteoarthritisRange of motionRehabilitationArthroplasty

Abstract

fetched live from OpenAlex

Background: Total knee arthroplasty (TKA) is a standard treatment for advanced osteoarthritis, yet the timing of postoperative rehabilitation remains debated. Early physiotherapy, started within 24 hours, is proposed to enhance mobility, reduce pain, and shorten hospital stay, whereas delayed physiotherapy, initiated after 48 hours, focuses on wound healing and pain control. Prior studies also support early mobilization for improved outcomes. This study compared early versus delayed physiotherapy following TKA in a tertiary care center in Gujarat, India. Materials and Methods: A prospective randomized controlled trial was conducted for one year at a tertiary hospital in Gujarat. Patients aged 50–75 years with unilateral TKA for primary osteoarthritis were randomized (1:1) into early physiotherapy (EP; <24 hours post-surgery) or delayed physiotherapy (DP; >48 hours). Interventions included standardized quadriceps strengthening, knee flexion/extension, and gait training, performed three times daily for 30–45 minutes. Patients with uncontrolled comorbidities or prior knee surgery were excluded. Outcomes were assessed at baseline, day 3, week 2, and month 3 using the Visual Analog Scale (VAS), goniometer-measured range of motion (ROM), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and length of stay (LOS). Ethical approval and informed consent were obtained. Results: A total of 100 patients (mean age 62.4 ± 7.2 years; 62% female) completed the study. Groups were comparable at baseline. EP patients reported lower VAS pain scores on day 3 (3.2 vs. 5.1; p<0.001), greater ROM at week 2 (85° vs. 72°; p<0.01), and improved WOMAC scores at month 3 (28.5 vs. 35.7; p=0.002). LOS was shorter in EP (4.8 vs. 6.3 days; p<0.001). Complication rates were similar. Conclusion: Early physiotherapy after TKA improves pain, ROM, function, and reduces LOS without added risk. Adoption in tertiary centers could enannce recovery and resource efficiency.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.040
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.171
GPT teacher head0.519
Teacher spread0.348 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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