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Record W4417397135 · doi:10.1093/jhered/esaf093

Genome assembly for the Sierra Nevada Parnassian ( <i>Parnassius behrii</i> ) and a brief review of butterfly genome sizes

2025· article· en· W4417397135 on OpenAlexfundno aff
Zachary G. MacDonald, Joseph N. Curti, Robert D. Cooper, Sean D. Schoville, Merly Escalona, Noravit Chumchim, Colin W Fairbairn, Erin Toffelmier, Courtney Miller, Mohan P A Marimuthu, Oanh Nguyen, William Seligmann, Thomas W. Gillespie, H. Bradley Shaffer

Bibliographic record

VenueJournal of Heredity · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsGenomeContigSequence assemblyGenome sizeGeneReference genomeButterfly

Abstract

fetched live from OpenAlex

The Sierra Nevada Parnassian (Parnassius behrii W.H. Edwards, 1870) (Lepidoptera: Papilionidae) is a high-elevation specialist butterfly endemic to the Sierra Nevada, California. We present a genome assembly for P. behrii, representing the first major genomic resource for the species and greater Parnassius phoebus species complex. The assembly consists of two haplotypes, 1.59 Gb and 1.46 Gb in length, with contig N50 values of 10.93 Mb and 11.84 Mb, scaffold N50 values of 52.56 Mb and 51.90 Mb, scaffold L50 values of 13 and 14, and BUSCO completeness scores of 98.7% and 94.4%, respectively. Both haplotypes are highly contiguous, with 31 chromosome-length scaffolds, including putative Z and W sex chromosomes. We annotated the genome with National Center for Biotechnology Information's (NCBI's) EGAPx pipeline, integrating database and novel transcript alignment with Hidden Markov Model-based gene predictions, yielding 17,191 genes with a BUSCO score of 98.1%. RepeatMasker identified that 26.68% (424.97 Mb) of the genome consists of repetitive elements. We also assembled a mitochondrial genome for P. behrii (15,391 bp) containing 2 rRNAs, 22 unique transfer RNAs, and 13 protein-coding genes. We finally reviewed 514 high-quality butterfly genomes available from the National Center for Biotechnology Information (NCBI). Parnassius species were observed to have the largest genomes, with P. behrii being the largest. This assembly provides a foundational resource for whole-genome research on P. behrii and the broader P. phoebus complex, enabling analyses of evolutionary differentiation, local adaptation, inbreeding, gene flow, taxonomy and conservation practices.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.935
Threshold uncertainty score0.405

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.264
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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