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Record W4417427059 · doi:10.3168/jds.2025-27134

Effects of supplementing a Bacillus-based direct-fed microbial on ex vivo fermentation traits and on performance of lactating Holstein dairy cows

2025· article· en· W4417427059 on OpenAlexfundno aff
À. Bach, Miguel Escartín, C. Culley, Jens N. Joergensen, O.C.M. Queiroz, Bruno I Cappellozza

Bibliographic record

VenueJournal of Dairy Science · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicRuminant Nutrition and Digestive Physiology
Canadian institutionsnot available
FundersFaculty of Arts and Social Sciences, Carleton University
KeywordsRumenFermentationDry matterPropionateHayStrawTotal mixed rationValerate

Abstract

fetched live from OpenAlex

Three studies evaluated the effects of a Bacillus -based direct-fed microbial (DFM) on ex vivo fermentation traits, as well as on performance of lactating dairy cows. In experiment 1, rumen-fistulated lactating Holstein-Friesian cows (6.6 ± 2.3 parity; 630 ± 37.2 kg BW; 18.9 ± 3.35 kg milk/d) were fed an unsupplemented ration (CON; n=5) or supplemented with 3 g/cow per d of a Bacillus -based DFM (BAC; n=5) for 14 d before rumen sampling and subsequent ex vivo evaluation of fermentation characteristics of 2 different substrates (vetch hay [ Vicia sativa ] and perennial ryegrass herbage [ Lolium perenne L.]). Total gas production, methane (CH 4 ), VFA, and rumen ammonia-N were determined after 24 h of fermentation. In experiment 2, 60 Holstein cows (mean ± SD; 61 ± 3 DIM) fed a 39:61 forage-to-concentrate TMR were assigned to CON or BAC (3 g/cow daily for 13 wk; n=30 cows per group). In experiment 3, 76 Holstein cows (25 ± 3 DIM) fed a 55:45 forage-to-concentrate TMR were assigned to CON or BAC (3 g/cow daily for 12 wk; n=38 cows per group). Dry matter intake, milk yield, milk composition, and feed efficiency were evaluated for both experiments 2 and 3. Data from all experiments were analyzed using mixed-effects models. In experiment 1, ruminal concentrations of total VFA, as well as molar proportions of butyrate, isovalerate, valerate, acetate-to-propionate ratio, and NH 3 -N increased in BAC compared with CON. In contrast, molar proportions of acetate and propionate were lower for BAC than for CON. Gas production was increased in BAC when adjusted for the amount of DM incubated without affecting CH 4 production. In experiment 2, DMI decreased for both groups starting at wk 7 of the study, but BAC cows consumed less feed than CON cows from wk 8 to 11 and at wk 13. As a consequence, feed efficiency was greater for BAC than for CON cows from wk 5 to 11 and at wk 13 of the study. In experiment 3, mean DMI, milk yield, ECM yield, and milk TS yield were greater in BAC than in CON cows. Altogether, these results indicate that feeding a Bacillus -based DFM is a feasible alternative to promote dairy cow productivity, likely through beneficial changes in ruminal fermentation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.250
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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