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Record W4417468190 · doi:10.52609/jmlph.v6i1.258

Clinical Practice Guidelines as Part of Evidence-Based Medicine and Related Legal Implications: An Analysis

2025· article· en· W4417468190 on OpenAlexvenueno aff
A. P. Rathnayake

Bibliographic record

VenueThe Journal of Medicine Law & Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicClinical practice guidelines implementation
Canadian institutionsnot available
Fundersnot available
KeywordsAutonomyContext (archaeology)Clinical PracticeMalpracticeBest practiceMEDLINEInformed consentHarmAlternative medicine

Abstract

fetched live from OpenAlex

‘Evidence-based medicine (EBM)’ describes the application of the best available scientific evidence in the treatment of patients. It is defined by the integration of best available research evidence with clinical expertise and patient values. A product of EBM is ‘clinical practice guidelines (CPG).’ Such guidelines include statements, informed by a systematic review of evidence, that outline recommendations to optimise patient care. The main focus of the present research is the use of clinical guidelines as a ‘standard of care’ in the context of medical malpractice litigation. Major challenges associated with the use of such guidelines include the multiplicity of guidelines for a given condition, and multimorbidity in patients (whereas guidelines typically address a single condition). Rigid adherence to CPG may also contribute to the erosion of professional autonomy and the development of ‘cookbook medicine’. Furthermore, concerning liability, the developers of such guidelines may be held indirectly liable, alongside professional caregivers, for harm incurred by patients. This paper adopts a qualitative methodology, including descriptive and critical analysis of the literature and case laws. Its findings recognise the potential of clinical guidelines to promote uniformity provided that ‘competent medical practice’, based on relevance, reliability, and authenticity, can overcome the issue of multiplicity. However, strict adherence to such guidelines is associated with the erosion of professional autonomy and professional judgement.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.072
metaresearch head score (Gemma)0.198
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.668
Threshold uncertainty score0.985

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0720.198
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.667
GPT teacher head0.656
Teacher spread0.011 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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