Lyophilized Bryndza cheese capsules increase butyrate-producing gut bacteria in recreational athletes: A randomized controlled trial
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Bryndza, a traditional sheep cheese from Eastern Europe, is a natural source of probiotic lactic acid bacteria (LAB). This study investigated the effects of encapsulated bryndza probiotic capsules on the gut microbiome and metabolome of young athletes. Recreational runners ( n = 26 experimental; n = 18 control) completed an 8-week intervention. Participants in the experimental group consumed Bryndza capsules. Stool samples and body composition were collected before and after intervention. Microbiota composition was analyzed by 16S rRNA gene sequencing, and fecal metabolites were measured using nuclear magnetic resonance spectroscopy. Bryndza capsules contained viable LAB, including Lacticaseibacillus paracasei , Lactococcus lactis , Leuconostoc mesenteroides , and Enterococcus species. No changes in body composition were observed. In the experimental group, butyrate-producing bacteria, such as Anaerostipes hadrus , Eubacterium ventriosum , and Faecalibacterium prausnitzii , increased significantly. Our findings indicate that lyophilized and encapsulated Bryndza retains probiotic activity and positively modulates the gut microbiome, particularly by enhancing butyrate-producing bacteria. • Encapsulated Bryndza preserved viability of traditional probiotic strains. • Bryndza capsules increased butyrate-producing gut bacteria in recreational runners. • Probiotic effect observed without increasing lactic acid bacteria in stool. • No coliform overgrowth confirmed microbiological safety of Bryndza capsules.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it