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Jaw-in-a-day (JIAD) for malignant indications: A systematic review

2025· article· en· W4417521828 on OpenAlexaff
Jessica Trac, Rashi Ramchandani, Leba M. Sarkis, Robert Calvisi, Noémie Villemure‐Poliquin, J Davies, Eszter Somogyi‐Ganss, Nick Blanas, Karl Cuddy, Danny Enepekides, Kevin Higgins, Justine Philteos, Antoine Eskander

Bibliographic record

VenueOral Oncology · 2025
Typearticle
Languageen
FieldMedicine
TopicBone health and treatments
Canadian institutionsSt. Michael's HospitalQueen's UniversitySunnybrook Health Science CentreToronto Rehabilitation InstituteSinai Health SystemUniversity of OttawaToronto East General HospitalUniversity of Toronto
Fundersnot available
KeywordsAdjuvant radiotherapyOsseointegrationRadiation therapyCancerProsthesisRadiation oncology

Abstract

fetched live from OpenAlex

INTRODUCTION: Jaw-in-a-day (JIAD) achieves resection, maxillofacial reconstruction and immediate dental rehabilitation. While increasingly used, evidence in oncologic populations remains limited. Our objective was to review JIAD in patients with head and neck cancer (HNC) and its outcomes. METHODS: Our systematic review was conducted following a predefined protocol (PROSPERO CRD420251043510). Our search strategy was executed on MEDLINE, Embase, CENTRAL, Web of Science, and CINAHL from January 2013 to October 2025. Studies with HNC patients of all ages who underwent JIAD were included. The Methodological Index for Non-Randomized Studies (MINORS) was used for risk of bias assessment. RESULTS: Nine studies were included with 57 patients. Common tumour characteristics included mandibular location (n = 31; 54.4 %) and squamous cell carcinoma pathology (n = 37; 64.9 %). A fibular free flap was used in all cases (n = 57; 100 %). Majority underwent adjuvant therapy (n = 36; 63.2 %). Prosthesis survival was reported in 6 studies (n = 25/32; 78.1 %) with follow-up periods ranging from 5 to 52 months. Prosthesis removal was commonly due to osteoradionecrosis (ORN) (n = 6; 10.5 %). All irradiated implants had successful early osseointegration (n = 99; 100 %). Delayed implant failure was reported in 4 patients (n = 4/36; 11.1 %) with 11 implants in radiotherapy field (n = 11/99; 11.1 %). CONCLUSION: JIAD for HNC patients can have high success in majority of select patients/defects. Although early osseointegration rates were high, oncologic patients receiving adjuvant radiation may remain at elevated risk for ORN-associated prosthesis failure. As such, the risks and benefits of JIAD should be carefully reviewed with the patient, and cancer staging should also be considered.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.852
Threshold uncertainty score0.245

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.417
Teacher spread0.379 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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