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Maternal postpartum depression modifies the association between maternal HIV infection and infant diarrhea in Ghana's Eastern region

2009· article· en· W46116797 on OpenAlexaff
Grace S. Marquis, Harriet Okronipa, Anna Lartey, Lucy Brakohiapa, Rafael Pérez‐Escamilla, Robert Mazur

Bibliographic record

VenueThe FASEB Journal · 2009
Typearticle
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsMcGill University
Fundersnot available
KeywordsMedicineDiarrheaIncidence (geometry)Human immunodeficiency virus (HIV)Depression (economics)ObstetricsPediatricsInternal medicineImmunology

Abstract

fetched live from OpenAlex

Diarrhea remains a major public health concern in low‐income countries. We examined the incidence and determinants of diarrhea among infants of HIV positive (HIV‐P), HIV negative (HIV‐N), and unknown HIV status (HIV‐U) women. Pregnant women (n=492) were recruited from three antenatal clinics after voluntary counselling and testing and followed from 0 to 12 mo after delivery. The incidence of diarrhea in the first 12 mo of life was 0.6 episodes per 100 d of observation; there was no group difference by maternal HIV‐status. Infants of HIV‐U compared to HIV‐P and HIV‐N women tended to have more days ill with diarrhea between 0‐3 mo (P=0.08), 3‐6 mo (P=0.06), and 0‐12 mo (P=0.05). HIV‐P compared to HIV‐N and HIV‐U women tended to report symptoms of post‐partum depression (PPD) at 0 mo (P=0.10). Infants whose mothers showed symptoms of PPD at 0 mo had over twice as many days ill with diarrhea (P<0.001) and more diarrheal episodes (P=0.002) between 0‐3 mo. Multivariate analyses showed that between 0‐3 mo of age, there was a significant interaction (P=0.02) between maternal HIV status and PPD. Symptoms of PPD at 0 mo increased the risk of 0‐3 mo diarrhea for HIV‐P (OR=6.2; 95% CI: 2.7, 14.3) and HIV‐U (OR=3.5; 95% CI: 1.9, 6.7) women, but not for HIV‐N women. Support systems in health care facilities should include program components that address PPD, especially in HIV‐affected communities. Funded by NICHD HD43260

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.296
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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