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Proximity-Graph-Based Tools for DNA Clustering

2009· book-chapter· en· W55831040 on OpenAlexaff
Imad Khoury, Godfried Toussaint, Antonio Ciampi

Bibliographic record

VenueIGI Global eBooks · 2009
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGene expression and cancer classification
Canadian institutionsMcGill University
Fundersnot available
KeywordsCluster analysisGraphComputer scienceTheoretical computer scienceVisualizationData pointCorrelation clusteringGraph drawingData miningMathematicsArtificial intelligencePattern recognition (psychology)

Abstract

fetched live from OpenAlex

Clustering is considered the most important aspect of unsupervised learning in data mining. It deals with finding structure in a collection of unlabeled data. One simple way of defining clustering is as follows: the process of organizing data elements into groups, called clusters, whose members are similar to each other in some way. Several algorithms for clustering exist (Gan, Ma, & Wu, 2007); proximity-graph-based ones, which are untraditional from the point of view of statisticians, emanate from the field of computational geometry and are powerful and often elegant (Bhattacharya, Mukherjee, & Toussaint, 2005). A proximity graph is a graph formed from a collection of elements, or points, by connecting with an edge those pairs of points that satisfy a particular neighbor relationship with each other. One key aspect of proximity-graph-based clustering techniques is that they may allow for an easy and clear visualization of data clusters, given their geometric nature. Proximity graphs have been shown to improve typical instance-based learning algorithms such as the k-nearest neighbor classifiers in the typical nonparametric approach to classification (Bhattacharya, Mukherjee, & Toussaint, 2005). Furthermore, the most powerful and robust methods for clustering turn out to be those based on proximity graphs (Koren, North, & Volinsky, 2006). Many examples have been shown where proximity-graph-based methods perform very well when traditional methods fail miserably (Zahn, 1971; Choo, Jiamthapthaksin, Chen, Celepcikay, Giusti, & Eick, 2007).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.019
Threshold uncertainty score0.065

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.012
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0100.010
Science and technology studies0.0020.002
Scholarly communication0.0040.004
Open science0.0040.006
Research integrity0.0030.005
Insufficient payload (model declined to judge)0.0190.016

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.268
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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