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Record W63388712 · doi:10.1096/fasebj.21.5.a705-a

B vitamin status and concentrations of homocysteine in Canadian women of childbearing age

2007· article· en· W63388712 on OpenAlexaffabout
Aysheh M. Shuaibi, James D. House, Gustaaf P. Sevenhuysen

Bibliographic record

VenueThe FASEB Journal · 2007
Typearticle
Languageen
FieldMedicine
TopicFolate and B Vitamins Research
Canadian institutionsCanadian Science Centre for Human and Animal HealthUniversity of Manitoba
Fundersnot available
KeywordsFortificationVitamin B12Folic acidMedicineFood fortificationDietary Reference IntakeFortified FoodHomocysteineVitaminFood scienceNeural tube defectVitamin CPregnancyNutrientEnvironmental healthBiologyEndocrinologyInternal medicineFetus

Abstract

fetched live from OpenAlex

Mandatory folic acid fortification of cereal‐grain products was introduced in 1998 to decrease the risk of having children with neural tube defects. Little is known about the vitamin B status of Canadian women of childbearing age after folic acid fortification era. The study objectives were to investigate folate, vitamin B6 and B12 status, and total homocysteine status, to investigate the existing pattern, and to estimate the contribution of folate intakes. Using a cross‐sectional study design, a fasting blood sample was obtained from 95 women at child bearing age. Dietary and supplemental intakes for nutrient were assessed. No women had biochemical evidence of folate deficiency, 5%six of ninety five of women were deficient in vitamin B6 and 3% had low vitamin B12, Hyperhomocysteinaemia > 12.0 μmol/l occurred in 2.1% of women. Dietary intake mean ± SD of food folic acid was 96 ± 63.9 μg/d, supplemental folic acid 94.9 ± 189.3 μg/d, the intake from natural folate 314.4± 134.3 μg/d, and the total intakes as DFES was 645.7±368.4 μg DFEs/d, derived mainly form bakery products (28%), vegetables (18%), pasta and rice (15%), juices (13%), milk and dairy products(6%), ready to eat cereal (5%). These data suggest that women of childbearing age are achieving positive folate balance and RBC concentrations associated with reduced risk of NTD following FA fortification of the food supply. Intakes of folic acid from fortified foods are within the level originally predicted for the fortification. Supported by Canadian Egg Marketing Agency and ARDI

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score0.057

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0020.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.282
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes2
Has abstractyes

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