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Record W6884746190 · doi:10.11886/scjsws20220228001

Psychometric properties of the MATRICS Consensus Cognitive Battery in young patients with bipolar disorder

2022· article· en· W6884746190 on OpenAlexaboutno aff

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2022
Typearticle
Languageen
FieldMedicine
TopicBipolar Disorder and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsBipolar disorderCognitionDiscriminant validityConfirmatory factor analysisPsychometricsVerbal memoryVerbal learningTest validityBipolar II disorder

Abstract

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ObjectiveTo investigate the psychometric features of MATRICS Consensus Cognitive Battery (MCCB) in adolescents with bipolar disorder, so as to evaluate its appropriateness for the measurement of cognitive deficits in adolescents with bipolar disorder.MethodsAdolescents with bipolar disorder (n=38), adolescents with major depressive episode (n=40) and healthy controls (n=41) matched on age, sex and educational background were enrolled. Adolescents with bipolar disorder were assessed using Montreal Cognitive Assessment Scale (MoCA) and MCCB at baseline and 2 weeks later, while the rest were only assessed using MCCB at baseline. Thereafter, the psychometric features of MCCB such as internal consistency, test-retest reliability and criterion-related validity, discriminant validity and structural validity were evaluated using Cronbach's α coefficient, Pearson correlation analysis, analysis of covariance and confirmatory factor analysis.Results①The Cronbach's α coefficient of MCCB in adolescents with bipolar disorder was 0.784 at baseline and 0.773 at two weeks later, respectively. ②Among adolescents with bipolar disorder, the test-retest reliability over a two-week interval of each dimension in MCCB ranged from 0.630 to 0.812 (P<0.01). ③ The criterion-related validity denoted that the score of short-term memory domain in MoCA was positively correlated with the speed of processing, verbal learning and working memory in MCCB (r=0.487, 0.522, P<0.05 or 0.01). ④ Discriminant validity analysis implied that the scores of the processing speed, attention/vigilance, working memory, verbal learning and memory, visual learning and memory, reasoning and problem solving in MCCB yielded statistical differences among adolescents with bipolar disorder, adolescents with major depressive episode and healthy controls (F=3.790~7.243, P<0.01). ⑤ Exploratory factor analysis showed that cumulative total variance contribution rate of MCCB amounted to 71.65% of four factors, and the confirmatory factor analysis indicated that the ideal 7-factor model had poor structural validity.ConclusionMCCB has good internal consistency, retest reliability and acceptable validity in adolescents with bipolar disorder.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.127
GPT teacher head0.446
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2022
Admission routes1
Has abstractyes

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