Additional file 4 of Consistent cord blood DNA methylation signatures of gestational age between South Asian and white European cohorts
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Additional file4 Figure S3. Relationship between CpG association effect size and heterogeneity of effect. Panel A) shows the scatterplot of estimated association effect in CHILD (x-axis) and START (y-axis) for CpGs that were significant in the meta-analysis (FDR adjusted p < 0.05) that also were heterogenous in their effects (Heterogeneous p < 0.01) (#CpG = 108); for the same set of CpGs, Panel B) shows the relationship between the absolute difference in beta-values (taken as the mean difference of CHILD and START) and the -log10 Wilcox test p-values, where Wilcox test p-value > 0.05 corresponded to no evidence for difference in distribution of CpG between CHILD and START, and those between 0.05 and 1×10–5, 1×10–5 and 1×10–10, and < 1×10–10 as small, medium and large difference. Each CpG that had been mapped to a gene using the “sesame” annotation package was labeled with the corresponding gene. The solid gray line is the best fitted line for the linear relationship between the effect sizes and the dashed gray line represents the reference of y=x
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.990 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it